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NCT03036605
The Effect of Dexamethasone Added to Bupivacain in Nasal Surgery
Phase 4 trial testing Bupivacaine in Nasal Surgery in 60 participants. Completed in 15 May 2017.
1 April 2017
Quick facts
| Lead sponsor | Ataturk University |
|---|---|
| Phase | Phase 4 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 60 |
| Start date | 15 March 2017 |
| Primary completion | 1 April 2017 |
| Estimated completion | 15 May 2017 |
| Sites | 1 location across Turkey (Türkiye) |
Drugs / interventions tested
- Bupivacaine (BUPIVACAINE) — full drug profile →
- Dexamethasone (dexamethasone) — full drug profile →
Conditions studied
- Nasal Surgery — all drugs for Nasal Surgery →
Sponsor
Ataturk University
Who can join
Adults 18 to 65, any sex, with Nasal Surgery. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Nasal packing is frequently applied after nasal surgery. Nasal packing reduces epistaxis, prevents septal hematoma and stabilizes nasal septum. Nasal mucosa is quite sensitive to pain, therefore the most common problems after surgery are postoperative pain and anxiety during removal of the nasal packing. Lots of methods have been tried to control this pain (non-steroidal anti-inflammatory drugs, nerve blockade with long-acting local anesthetics, local anesthetics infiltration into nasal packing). Glucocorticoids have been used as an adjuvant in the management of acute postoperative pain. Perineural dexamethasone as an adjuvant for the single-injection nerve block can prolong analgesia and reduce opioid-requiring after surgery. Furthermore dexamethasone reduces postoperative nausea and vomiting incidance.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT03036605
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Other recruiting trials for Nasal Surgery
Currently open trials in the same condition.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03036605 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Ataturk University
- Last refreshed: 7 June 2017
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03036605.
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