Last reviewed · How we verify
NCT07253428: Sugamadex
Emergence Agitation
NA trial testing Neostigmine + Atropine in Emergence Agitation in 486 participants. Participants enrolled and being followed up; not accepting new ones.
31 December 2025
Quick facts
| Lead sponsor | Ain Shams University |
|---|---|
| Phase | NA |
| Status | Active, enrolled |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | prevention |
| Enrollment | 486 |
| Start date | 30 October 2025 |
| Primary completion | 31 December 2025 |
| Estimated completion | 31 January 2026 |
| Sites | 1 location across Saudi Arabia |
Drugs / interventions tested
- Neostigmine + Atropine — full drug profile →
- Sugamadex — full drug profile →
Conditions studied
- Emergence Agitation — all drugs for Emergence Agitation →
- Nasal Surgery — all drugs for Nasal Surgery →
Sponsor
Ain Shams University
Who can join
Adults 18 to 60, any sex, with Emergence Agitation or Nasal Surgery. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The impact of sugammadex on agitation upon emergence following adult nasal surgeries is an issue which needs to be studied that links anesthetic management with postoperative recovery.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07253428
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Neostigmine + Atropine
Trials testing the same drug.
- NCT07271875 — Neuromuscular Blocking Agents on Gastrointestinal Function Following Colorectal Surgery · Phase 3 · not yet recruiting
- NCT06632067 — Sugammadex and Time to Extubation in Ophthalmic Surgery · completed
- NCT03909165 — Efficacy, Safety, and Pharmacokinetics of Sugammadex (MK-8616) for Reversal of Neuromuscular Blockade in Pediatric Parti · Phase 4 · completed
- NCT03351608 — Efficacy, Safety, and Pharmacokinetics of Sugammadex for Reversal of Neuromuscular Blockade (NMB) in Pediatric Participa · Phase 4 · completed
Other recruiting trials for Emergence Agitation
Currently open trials in the same condition.
- NCT07523438 — Effect of Intranasal Dexmedetomidine on the Incidence of Emergence Agitation in Children Undergoing Strabismus Surgery · NA · recruiting
- NCT07389135 — Heart Rate Variability and Anxiety as Predictors of Emergence Agitation After Septorhinoplasty · recruiting
- NCT07348497 — Effects of Preoperative Education on Anxiety and Emergence Agitation · NA · active not recruiting
- NCT07435675 — Efficacy of Ultrasound-guided Greater Auricular Nerve Block in Preventing Postoperative Emergence Agitation in Pediatric · NA · recruiting
- NCT07345715 — Oral Melatonin Versus Nebulized Dexmedetomidine on Emergence Agitation in Children Undergoing Adenotonsillectomy · NA · recruiting
Other Ain Shams University trials
Trials by the same sponsor.
- NCT07435493 — Fentanyl Versus Opioid Free Multimodal Analgesia for Perioperative Pain Control in Children With Mild to Moderate Obstru · NA · not yet recruiting
- NCT07482540 — Role of Dexmedatomidine Drug in Prevention of Atrial Fibrillations Post Mitral Valve Surgery · NA · not yet recruiting
- NCT07531030 — Posterior Pericapsular Deep Gluteal Block Combined With Pericapsular Nerve Group and Lateral Femoral Cutaneous Nerve Blo · NA · not yet recruiting
- NCT06839027 — Arterial to Central co2gap in Relation to Outcome After Cardiopulmonary Bypass · not yet recruiting
- NCT07516535 — DISS vs FANS in Suction-Assisted RIRS for Medium-Sized Renal Stones · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07253428 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Ain Shams University
- Last refreshed: 28 November 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07253428.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing