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NCT03035084
Is Vitamin D2 Treatment-associated Decrease in 25(OH)D3 Level a Reciprocal Phenomena?
Phase 4 trial testing Vitamin D3 in Vitamin D Deficiency in 100 participants. Completed in 20 November 2017.
20 November 2017
Quick facts
| Lead sponsor | King Faisal Specialist Hospital & Research Center |
|---|---|
| Phase | Phase 4 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | triple |
| Primary purpose | basic science |
| Enrollment | 100 |
| Start date | 15 February 2017 |
| Primary completion | 20 November 2017 |
| Estimated completion | 20 November 2017 |
| Sites | 1 location across Saudi Arabia |
Drugs / interventions tested
- Vitamin D3 (cholecalciferol) — full drug profile →
- Vitamin D2 — full drug profile →
- Placebo oral capsule
Conditions studied
- Vitamin D Deficiency — all drugs for Vitamin D Deficiency →
- 25-Hydroxyvitamin D Concentration — all drugs for 25-Hydroxyvitamin D Concentration →
Sponsor
King Faisal Specialist Hospital & Research Center
Who can join
18 and older, any sex, with Vitamin D Deficiency or 25-Hydroxyvitamin D Concentration. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Several studies have demonstrated that D2 treatment is associated with a decrease in 25(OH)D3 level and therefore have proposed that D3 would be preferable in term of raising total 25(OH)D level. The investigators postulate that the D2 treatment-associated decrease in 25(OH)D3 level may be related to an increase in total 25(OH)D level rather than being specific to D2 treatment, and thus there would be a D3 treatment-associated decrease in 25(OH)D2 level. The investigators plan to conduct a double-blind placebo-controlled trial to examine the effect of D3 treatment on 25(OH)D2 level and the effect of D2 treatment on 25(OH)D3 leve
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Vitamin-D2 treatment-associated decrease in 25(OH)D3 level is a reciprocal phenomenon: a randomized controlled trial.
Hammami MM, Abuhdeeb K, Hammami S, Yusuf A. · · 2019 · cited 17× · PMID 30658603 · DOI 10.1186/s12902-019-0337-8
Verify or expand the search:
- PubMed search for NCT03035084
- Europe PMC full search
- ASCO Meeting Library
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Other recruiting trials for Vitamin D Deficiency
Currently open trials in the same condition.
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Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03035084 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by King Faisal Specialist Hospital & Research Center
- Last refreshed: 13 August 2018
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03035084.
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