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NCT02971254
The Effects of Inhalational Anaesthetics in Cognitive Functions in Down Syndrome Patients
Phase 2 trial testing Sevoflurane in Down Syndrome in 39 participants. Completed in 30 May 2019.
6 January 2019
Quick facts
| Lead sponsor | Asklepieion Voulas General Hospital |
|---|---|
| Phase | Phase 2 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | supportive care |
| Enrollment | 39 |
| Start date | 1 December 2016 |
| Primary completion | 6 January 2019 |
| Estimated completion | 30 May 2019 |
| Sites | 1 location across Greece |
Drugs / interventions tested
- Sevoflurane — full drug profile →
- Desflurane (DESFLURANE) — full drug profile →
Conditions studied
- Down Syndrome — all drugs for Down Syndrome →
Sponsor
Asklepieion Voulas General Hospital
Who can join
Adults 16 to 75, any sex, with Down Syndrome. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Recovery of the cognitive functions and recovery features after general anaesthesia in Down syndrome patients. A comparison of Sevoflurane and Desflurane.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
The impact of inhalation anesthetics on early postoperative cognitive function and recovery characteristics in Down syndrome patients: a randomized, double - blind study.
Gkliatis E, Makris A, Staikou C. · · 2021 · cited 2× · PMID 34535086 · DOI 10.1186/s12871-021-01447-x
Verify or expand the search:
- PubMed search for NCT02971254
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
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Other recruiting trials for Down Syndrome
Currently open trials in the same condition.
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Other Asklepieion Voulas General Hospital trials
Trials by the same sponsor.
- NCT06600386 — Individualized Intraoperative PEEP Following Alveolar Recruitment Maneuvres and Postoperative Respiratory Complications · Phase 2 · completed
- NCT03428633 — Thoracic Paravertebral Blocks in Open Nephrectomy · Phase 2 · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT02971254 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Asklepieion Voulas General Hospital
- Last refreshed: 9 June 2020
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02971254.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing