Who is sponsoring NCT02950116?

NCT02950116 is sponsored by Universitair Ziekenhuis Brussel.

What drugs are being tested in NCT02950116?

Interventions in NCT02950116: Perform three multiple breath nitrogen washout tests (N2-MBW-test).

What condition does NCT02950116 study?

NCT02950116 studies Asthma, Bronchiectasis, Cystic Fibrosis.

Is NCT02950116 still recruiting?

NCT02950116 is currently terminated. Last updated 20 June 2017.

Last reviewed 2017-06-20 · How we verify

NCT02950116

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Lung Clearance Index (LCI) in Pediatric Patients With Obstructive Lung Disease

Terminated NA Last updated 20 June 2017

What this trial tests

NA trial testing Perform three multiple breath nitrogen washout tests (N2-MBW-test) in Asthma in 27 participants. Terminated before completion.

Timeline

9 March 2017

Primary endpoint
31 March 2017

7 April 2017

Quick facts

Lead sponsor	Universitair Ziekenhuis Brussel
Phase	NA
Status	Terminated
Study type	INTERVENTIONAL
Allocation	non randomized
Design	parallel
Masking	none
Primary purpose	diagnostic
Enrollment	27
Start date	9 March 2017
Primary completion	31 March 2017
Estimated completion	7 April 2017
Sites	1 location across Belgium

Drugs / interventions tested

Perform three multiple breath nitrogen washout tests (N2-MBW-test)

Conditions studied

Asthma — all drugs for Asthma →
Bronchiectasis — all drugs for Bronchiectasis →
Cystic Fibrosis — all drugs for Cystic Fibrosis →

Sponsor

Universitair Ziekenhuis Brussel — full company profile →

Who can join

Adults 6 to 17, any sex, with Asthma or Bronchiectasis. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Chronic respiratory diseases (CRDs) affect the airways and other structures of the lungs and thereby lead to ventilation inhomogeneity. The most common CRDs in children are asthma, bronchiectasis and cystic fibrosis (CF). All three are obstructive diseases. However, while asthma is mostly characterized by obstruction due to bronchoconstriction of the airways, obstruction in bronchiectasis and CF originates primarily from mucus retention due to abnormal airway clearance mechanisms. The Nitrogen Multiple Breath Washout test (N2-MBW-test) is a robust and sensitive detector of early pulmonary changes and ventilation inhomogeneity. The minimal cooperation which is required for this test makes it very convenient for use in any age category. Research on LCI described it as a reliable indicator of obstructive lung disease in pediatric CF patients as from 6 years of age. Whether LCI is a reliable parameter for early lung disease in asthma children is less clearly demonstrated. No data were found on LCI calculated from the N2-MBW-test in children with bronchiectasis.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

Verify or expand the search:

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Other Universitair Ziekenhuis Brussel trials

Trials by the same sponsor.

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Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT02950116 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Universitair Ziekenhuis Brussel
Last refreshed: 20 June 2017

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02950116.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing