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NCT02949245
Neurologic Complications in Spinal Deformity Surgery - Extension
trial testing Interventions in Adult Spinal Deformity in 77 participants. Completed in 28 December 2019.
28 December 2019
Quick facts
| Lead sponsor | AO Foundation, AO Spine |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 77 |
| Start date | 17 August 2017 |
| Primary completion | 28 December 2019 |
| Estimated completion | 28 December 2019 |
| Sites | 11 locations across Japan, United Kingdom, Canada, China, United States, Spain |
Drugs / interventions tested
- Interventions
Conditions studied
- Adult Spinal Deformity — all drugs for Adult Spinal Deformity →
Sponsor
AO Foundation, AO Spine
Who can join
Adults 18 to 80, any sex, with Adult Spinal Deformity. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
272 subjects with "high risk" adult spinal deformity requiring surgical correction were enrolled in the previous prospective multi-center international Scoli-RISK-1 study. "High risk" patients were defined by either their diagnoses and/or the type of surgical intervention as listed in the inclusion criteria. Neurological complications in the form of new motor and sensory deficits were monitored prospectively in all patients at hospital discharge, at 6 weeks (± 2 weeks), 6 months (± 2 months) and 24 months (± 2 months) after the surgery. The relationship to the surgical intervention was assessed in all new deficits. Regression analyses were used to evaluate the association between patient demographics, co-morbidities, treatment history, spinal deformity characteristics, surgical characteristics, non-neurologic complications and pre-surgical status to occurrence of a neurologic deficit after surgery. All enrolled Scoli-RISK-1 participants will be re-consented and asked to return for a 5 year FU visit.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
The AO Spine Knowledge Forums: A Decade of Impactful Spine Research.
Schnake KJ, Fehlings MG, Germscheid N, Kurpad S, et al · · 2025 · PMID 40484860 · DOI 10.1177/21925682251343521
Verify or expand the search:
- PubMed search for NCT02949245
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other recruiting trials for Adult Spinal Deformity
Currently open trials in the same condition.
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- NCT04194138 — Complex Adult Deformity Surgery (CADS) · recruiting
Other AO Foundation, AO Spine trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT02949245 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by AO Foundation, AO Spine
- Last refreshed: 19 May 2020
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02949245.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing