NCT02925962: CDSSR18

Evaluation of an Electronic CKD Clinical Decision Support System (CDSS) in Clinical Care

Completed NA Last updated 12 August 2020

What this trial tests

NA trial testing Clinical Decision Support System (CDSS) in Hypertension in 542 participants. Completed in 30 June 2020.

Timeline

14 August 2017

Primary endpoint
4 October 2018

30 June 2020

Quick facts

Lead sponsor	University of California, San Francisco
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	screening
Enrollment	542
Start date	14 August 2017
Primary completion	4 October 2018
Estimated completion	30 June 2020
Sites	1 location across United States

Drugs / interventions tested

• Clinical Decision Support System (CDSS)
• Clinic Decision Sup System + Pharmacist

Conditions studied

• Hypertension — all drugs for Hypertension →
• Renal Insufficiency, Chronic — all drugs for Renal Insufficiency, Chronic →

Sponsor

University of California, San Francisco

Who can join

Adults 18 to 80, any sex, with Hypertension or Renal Insufficiency, Chronic. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The investigators propose a three-arm, pragmatic, cluster-randomized clinical trial based in primary care. Participating Primary Care Providers (PCPs) will be randomized to usual care or one of two intervention arms. The first intervention will evaluate the efficacy of an automated CDSS that utilizes the electronic health record (EHR) to facilitate triple marker test ordering, guideline implementation and BP management, compared with usual care, among patients with previous documentation of eGFRcreat \<60 ml/min/1.73m2. The second intervention goes a step further, and will evaluate whether a CDSS plus a follow-up telephone call from a pharmacist (CDSS PLUS) can improve BP management and patient CKD and NSAID toxicity knowledge among the patients with CKD, compared with CDSS alone. The primary clinical outcome is BP level, with secondary outcomes related to processes of care and patient knowledge.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

1. Electronic Decision Support for Management of CKD in Primary Care: A Pragmatic Randomized Trial.
   Peralta CA, Livaudais-Toman J, Stebbins M, Lo L, et al · · 2020 · cited 47× · PMID 32682696 · DOI 10.1053/j.ajkd.2020.05.013
2. A Pragmatic Cluster Randomized Trial of an Electronic Clinical Decision Support System to Improve Chronic Kidney Disease Management in Primary Care: Design, Rationale, and Implementation Experience.
   Khoong EC, Karliner L, Lo L, Stebbins M, et al · · 2019 · cited 12× · PMID 31199334 · DOI 10.2196/14022