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NCT02856165: BRONCHOPTI
High-flow Nasal Oxygen Therapy in Hospitalized Infant With Moderate-to-severe Bronchiolitis
NA trial testing High-flow nasal canula oxygen therapy in Bronchiolitis in 268 participants. Completed in 23 November 2017.
15 November 2017
Quick facts
| Lead sponsor | Assistance Publique - Hôpitaux de Paris |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | supportive care |
| Enrollment | 268 |
| Start date | 28 October 2016 |
| Primary completion | 15 November 2017 |
| Estimated completion | 23 November 2017 |
| Sites | 1 location across France |
Drugs / interventions tested
- High-flow nasal canula oxygen therapy
- Low-flow oxygen therapy with standard nasal canula
Conditions studied
- Bronchiolitis — all drugs for Bronchiolitis →
Sponsor
Assistance Publique - Hôpitaux de Paris — full company profile →
Who can join
Adults 7 Days to 6 Months, any sex, with Bronchiolitis. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Over the last decade, high-flow nasal oxygen therapy (HFN) has emerged as a new method to provide respiratory support in children with moderate to severe bronchiolitis. However, any randomized clinical trial (RCT) have demonstrated that earlier support with HFN is superior to standard care including low -flow nasal oxygen therapy to reduce the risk of acute respiratory failure requiring non invasive (or tracheal) ventilation and subsequently the need of PICU transfer.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
High-flow nasal cannula therapy for infants with bronchiolitis.
Armarego M, Forde H, Wills K, Beggs SA. · · 2024 · cited 15× · PMID 38506440 · DOI 10.1002/14651858.cd009609.pub3 -
Decision-making in acute viral bronchiolitis: A universal guideline and a publication gap.
Meyburg J, Ries M. · · 2020 · cited 2× · PMID 32810169 · DOI 10.1371/journal.pone.0237801
Verify or expand the search:
- PubMed search for NCT02856165
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Bronchiolitis
Currently open trials in the same condition.
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- NCT06862895 — Effect of Chest Physiotherapy on Clinical Outcome of Infants With Bronchiolitis · NA · recruiting
- NCT06842238 — Descriptive Study of the Initial Management of Young Children With Moderate Acute BRONCHiotitis With Home Hospitalisatio · recruiting
- NCT06425107 — Point-of-Care Lung Ultrasound for Prognosis in Critically Ill Infants With Acute Lower Respiratory Tract Infection · recruiting
- NCT06108648 — Efficacy of Lavender Essential Oil Chest Wraps in Infants With Bronchiolitis · Phase 4 · recruiting
Other Assistance Publique - Hôpitaux de Paris trials
Trials by the same sponsor.
- NCT07443436 — Immunomodulatory Treatment of Interstitial Lung Disease Associated With Surfactant Related Gene Variants · Phase 2 · not yet recruiting
- NCT07499492 — Red Blood Cell Transfusion to Optimize Extubation · NA · not yet recruiting
- NCT07379918 — Real-life Evaluation of Endopredict® in Early HR+/HER2- Breast Cancer · recruiting
- NCT07473869 — Smartphone Application for Automated Measurement of Capillary Refill Time (CRT) · not yet recruiting
- NCT07505394 — Efficacy of a Prediction Model-based Algorithm to PREVENT Drug-induced Impulse Control Disorders in Parkinson's Disease · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT02856165 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Assistance Publique - Hôpitaux de Paris
- Last refreshed: 30 April 2018
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02856165.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing