NCT02832336 is a Phase 1, PHASE2 clinical trial of Vivarin in Narcolepsy, sponsored by King Saud University.

Who is sponsoring NCT02832336?

NCT02832336 is sponsored by King Saud University.

What drugs are being tested in NCT02832336?

Interventions in NCT02832336: Vivarin, Fiber.

What condition does NCT02832336 study?

NCT02832336 studies Narcolepsy.

Is NCT02832336 still recruiting?

NCT02832336 is currently completed. Last updated 1 March 2019.

Last reviewed 2019-03-01 · How we verify

NCT02832336

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

The Effect of Caffeine on the Narcoleptic Patients

Completed Phase 1, PHASE2 Last updated 1 March 2019

What this trial tests

Phase 1, PHASE2 trial testing Vivarin in Narcolepsy in 16 participants. Completed in 7 May 2018.

Timeline

1 October 2016

Primary endpoint
11 May 2017

7 May 2018

Quick facts

Lead sponsor	King Saud University
Phase	Phase 1, PHASE2
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	supportive care
Enrollment	16
Start date	1 October 2016
Primary completion	11 May 2017
Estimated completion	7 May 2018
Sites	1 location across Saudi Arabia

Drugs / interventions tested

Vivarin — full drug profile →
Fiber — full drug profile →

Conditions studied

Narcolepsy — all drugs for Narcolepsy →

Sponsor

King Saud University

Who can join

Adults 18 to 45, any sex, with Narcolepsy. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Caffeine may be playing a beneficial role in patients with narcolepsy. However, the relationship between caffeine and its effects on narcoleptic patients has not been examined, and it is also unclear whether caffeine provides a beneficial effect or not. Hence, the aim of this study is to assess the effects of caffeine consumption on daytime sleepiness and reaction time in narcoleptic patients.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

The hypoxia-adenosine link during inflammation.
Bowser JL, Lee JW, Yuan X, Eltzschig HK. · · 2017 · cited 90× · PMID 28798196 · DOI 10.1152/japplphysiol.00101.2017
The effects of caffeine on drowsiness in patients with narcolepsy: a double-blind randomized controlled pilot study.
Aldosari MS, Olaish AH, Nashwan SZ, Abulmeaty MMA, et al · · 2020 · cited 4× · PMID 32215834 · DOI 10.1007/s11325-020-02065-6

Verify or expand the search:

Other recruiting trials for Narcolepsy

Currently open trials in the same condition.

NCT06797284 — The Impact of Light, Electrical, and Magnetic Neuroregulation Interventions on Sleep-wake Disorders · NA · recruiting
NCT06586138 — Study of Psychological, Sociological and Professional Factors Associated With Maintenance of Wakefulness Test · recruiting
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NCT05615584 — Spectrometry (MRM) Versus I 125 Radioimmunoassay (RIA) for Quantification of Orexin-A of Patients With Hypersomnolence · NA · recruiting
NCT06279247 — Proteomics and Metabolomics of Body Fluid in Patients With Narcolepsy · recruiting

Other King Saud University trials

Trials by the same sponsor.

NCT07500493 — Tele-Rehabilitation in Adults With Cystic Fibrosis · NA · not yet recruiting
NCT07324044 — Chrono-ALIGN: A Chronotype-Based Chrono-Nutrition Intervention in Post-Bariatric Patients · NA · not yet recruiting
NCT07288385 — Investigating the Feasibility of Combining Virtual Reality and Bilateral Transcranial Direct Stimulation to Improve Uppe · NA · recruiting
NCT07475195 — Oral Probiotics and Denture Care in Saudi Arabia: Evaluating Knowledge, Practices, and the Future of Innovative Hygiene · completed
NCT07159152 — Effects of Coffee Versus Hibiscus Tea Consumption During Prolonged Sitting on Blood Pressure and Heart Rate · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT02832336 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by King Saud University
Last refreshed: 1 March 2019

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02832336.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing