NCT02825654 (SHADE) is a clinical trial in Pulmonary Function, sponsored by VA Office of Research and Development.

Who is sponsoring NCT02825654?

NCT02825654 is sponsored by VA Office of Research and Development.

What condition does NCT02825654 study?

NCT02825654 studies Pulmonary Function.

Is NCT02825654 still recruiting?

NCT02825654 is currently enrolling by invitation. Last updated 6 November 2025.

Last reviewed 2025-11-06 · How we verify

NCT02825654: SHADE

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Service and Health Among Deployed Veterans

ENROLLING BY INVITATION Last updated 6 November 2025

What this trial tests

trial in Pulmonary Function in 6,200 participants. Enrolling by invitation.

Timeline

8 March 2018

Primary endpoint
30 June 2027

30 June 2029

Quick facts

Lead sponsor	VA Office of Research and Development
Status	ENROLLING BY INVITATION
Study type	OBSERVATIONAL
Enrollment	6,200
Start date	8 March 2018
Primary completion	30 June 2027
Estimated completion	30 June 2029
Sites	6 locations across United States

Conditions studied

Pulmonary Function — all drugs for Pulmonary Function →

Sponsor

VA Office of Research and Development — full company profile →

Who can join

Eligibility, any sex, with Pulmonary Function. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The purpose of the study is to better understand the health, including lung health, of Veterans who deployed in support of Operation Enduring Freedom (OEF), Operation Iraqi Freedom (OIF), or Operation New Dawn (OND) and other deployments following these Operations.

Publications & conference data

7 peer-reviewed publications reference this trial (live from Europe PMC):

Respiratory Health after Military Service in Southwest Asia and Afghanistan. An Official American Thoracic Society Workshop Report.
Garshick E, Abraham JH, Baird CP, Ciminera P, et al · · 2019 · cited 63× · PMID 31368802 · DOI 10.1513/annalsats.201904-344ws
Chronic respiratory symptoms following deployment-related occupational and environmental exposures among US veterans.
Garshick E, Redlich CA, Korpak A, Timmons AK, et al · · 2024 · cited 16× · PMID 37968126 · DOI 10.1136/oemed-2023-109146
Current understanding of the impact of United States military airborne hazards and burn pit exposures on respiratory health.
Trembley JH, Barach P, Tomáška JM, Poole JT, et al · · 2024 · cited 13× · PMID 39434148 · DOI 10.1186/s12989-024-00606-5
Sinusitis and rhinitis among US veterans deployed to Southwest Asia and Afghanistan after September 11, 2001.
Maccarone J, Redlich CA, Timmons A, Korpak AM, et al · · 2025 · cited 4× · PMID 39659739 · DOI 10.1016/j.jacig.2024.100367
Deployment-related Cigarette Smoking Behaviors and Pulmonary Function Among U.S. Veterans.
Maccarone JR, Sterns OR, Timmons A, Korpak AM, et al · · 2024 · cited 4× · PMID 38536226 · DOI 10.1093/milmed/usae049
Civilian Occupational Exposure to Vapors, Gas, Dust, or Fumes and Respiratory Health Among United States Military Veterans.
Mohazzab-Hosseinian S, Redlich CA, Korpak AM, Timmons AKI, et al · · 2026 · PMID 42028841 · DOI 10.1002/ajim.70083
Exposures to combustion sources near military operations in Iraq and Afghanistan using satellite observations.
Franklin M, Yin X, Korpak A, Blanc PD, et al · · 2025 · PMID 41073689 · DOI 10.1038/s41370-025-00804-z

Verify or expand the search:

Other recruiting trials for Pulmonary Function

Currently open trials in the same condition.

NCT07380789 — Comprehensive Multicenter Study on the Management of Acute Pain Following Thoracic Combat-Related Trauma in Ukraine · NA · recruiting
NCT07196436 — Asthma Intervention With Residential Ventilation and Air Cleaner (AIRVAC) Study · NA · recruiting
NCT06961838 — The Effect of Inspiratory Muscle Training With Substance Use Disorder · NA · recruiting
NCT07112703 — Effect of Incentive Respiratory Training on Pulmonary Functions and Functional Capacity in Children With B-thalassemia M · NA · recruiting
NCT06477458 — Deep Learning for Preoperative Pulmonary Assessment in Thoracic CT · recruiting

Other VA Office of Research and Development trials

Trials by the same sponsor.

NCT07456150 — Personalizing Veteran Pain Care: Adapting Coaching Interventions to Support Maintenance of Self-Care · Phase 1 · not yet recruiting
NCT06746727 — The Development of a Transdiagnostic Intervention to Improve Social Functioning and Intimate Relationships Among Veteran · NA · not yet recruiting
NCT07362576 — Perinatal Peer Support for Veterans With Serious Mental Illness · NA · not yet recruiting
NCT06766331 — Integrated Care Versus Usual Care for Opioid Use Disorder and Infectious Diseases in Veterans · NA · not yet recruiting
NCT07397195 — ACT for Veterans With IBD and Mental Health Challenges · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT02825654 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by VA Office of Research and Development
Last refreshed: 6 November 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02825654.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing