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NCT02752737
Cryo Global Registry
Completed
Last updated 30 July 2025
What this trial tests
trial in Atrial Fibrillation in 5,385 participants. Completed in 29 November 2024.
Timeline
2 May 2016
Primary endpoint
29 November 2024
29 November 2024
29 November 2024
Quick facts
| Lead sponsor | Medtronic Cardiac Ablation Solutions |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 5,385 |
| Start date | 2 May 2016 |
| Primary completion | 29 November 2024 |
| Estimated completion | 29 November 2024 |
| Sites | 163 locations across Italy, Colombia, Japan, Malaysia, Kazakhstan, Taiwan, Poland, South Korea |
Conditions studied
- Atrial Fibrillation — all drugs for Atrial Fibrillation →
Sponsor
Medtronic Cardiac Ablation Solutions — full company profile →
Who can join
18 and older, any sex, with Atrial Fibrillation. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Cryo Global Registry a prospective, global, multi-center, observational Post-Market Registry
Publications & conference data
8 peer-reviewed publications reference this trial (live from Europe PMC):
-
Safety and efficacy of cryoballoon ablation for the treatment of paroxysmal and persistent AF in a real-world global setting: Results from the Cryo AF Global Registry.
Chun KRJ, Okumura K, Scazzuso F, Keun On Y, et al · · 2021 · cited 28× · PMID 33850577 · DOI 10.1002/joa3.12504 -
Cryoballoon Ablation for the Treatment of Atrial Fibrillation in Patients With Concomitant Heart Failure and Either Reduced or Preserved Left Ventricular Ejection Fraction: Results From the Cryo AF Global Registry.
Rordorf R, Scazzuso F, Chun KRJ, Khelae SK, et al · · 2021 · cited 19× · PMID 34889108 · DOI 10.1161/jaha.121.021323 -
Cryoballoon ablation for paroxysmal atrial fibrillation in Japan: 2-year safety and efficacy results from the Cryo AF Global Registry.
Kimura M, Kobori A, Nitta J, Hirao K, et al · · 2022 · cited 11× · PMID 35119586 · DOI 10.1007/s10840-022-01132-0 -
Impact of first-line cryoablation for atrial fibrillation on healthcare utilization, arrhythmia disease burden and efficacy outcomes: real-world evidence from the Cryo Global Registry.
Zucchelli G, Chun KRJ, Khelae SK, Földesi C, et al · · 2023 · cited 7× · PMID 36331681 · DOI 10.1007/s10840-022-01388-6 -
Cryoballoon ablation of atrial fibrillation in octogenarians: one year outcomes from the cryo global registry.
Lawin D, Lawrenz T, Chun KRJ, Lim HE, et al · · 2024 · cited 6× · PMID 38082096 · DOI 10.1007/s10840-023-01680-z -
Cryoballoon Catheter Ablation in Korean Patients With Paroxysmal and Persistent Atrial Fibrillation: One Year Outcome From the Cryo Global Registry.
Lim HE, Oh IY, Kueffer FJ, van Bragt KA, et al · · 2022 · cited 6× · PMID 36097833 · DOI 10.4070/kcj.2022.0127 -
Impact of atrial fibrillation diagnosis-to-ablation time on 24-month efficacy and safety outcomes in the Cryo Global Registry.
Lawin D, Stellbrink C, Chun KJ, Li CH, et al · · 2025 · cited 5× · PMID 39836630 · DOI 10.1093/europace/euaf008 -
Regional variations in patient selection and procedural characteristics for cryoballoon ablation of atrial fibrillation in the cryo global registry.
Scazzuso F, Ptaszyński P, Kaczmarek K, Chun KRJ, et al · · 2024 · cited 3× · PMID 37505337 · DOI 10.1007/s10840-023-01582-0
Verify or expand the search:
- PubMed search for NCT02752737
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Atrial Fibrillation
Currently open trials in the same condition.
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Other Medtronic Cardiac Ablation Solutions trials
Trials by the same sponsor.
- NCT07298473 — Conquer-AF Protocol for Redo Ablation Procedures in Recurrent Paroxysmal and Persistent Atrial Fibrillation Using the Sp · NA · recruiting
- NCT07308847 — Horizon 360 Protocol for the Treatment of Paroxysmal Atrial Fibrillation With the Sphere-360™ Catheter and Affera™ Mappi · NA · recruiting
- NCT06578104 — PULSED AF Post-Approval Study · recruiting
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- NCT06026345 — Affera Global Registry · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
Data sources for this page
- Trial protocol + status: ClinicalTrials.gov NCT02752737 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Medtronic Cardiac Ablation Solutions
- Last refreshed: 30 July 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02752737.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing