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NCT02742506: MUSICOREVEIL
Beneficial Effects of Music on Cognition and Consciousness Level
NA trial testing Electroencephalography (EEG) in Coma in 86 participants. Completed in 23 October 2019.
23 October 2019
Quick facts
| Lead sponsor | Hospices Civils de Lyon |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | non randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | other |
| Enrollment | 86 |
| Start date | 25 June 2013 |
| Primary completion | 23 October 2019 |
| Estimated completion | 23 October 2019 |
| Sites | 1 location across France |
Drugs / interventions tested
- Electroencephalography (EEG)
Conditions studied
- Coma — all drugs for Coma →
Sponsor
Hospices Civils de Lyon — full company profile →
Who can join
Adults 18 to 80, any sex, with Coma. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Exposure to music improves cognitive function in 'healthy' participants and in brain-damaged patients. However, it is still difficult to understand what precisely in music causes a positive effect : are they emotional components, familiarity or preference which improve cognition or is there any specific effect of music? Moreover, it is not yet possible to characterize the neural and functional links between the brain systems solicited by music and those associated with other cognitive functions enhanced by music. Finally, researches on brain-damaged patients have not exploited the potential effect of music on the level of alert and perceptual awareness, while this type of stimulation could be a valuable tool to improve cognition in patients with a disturbance of consciousness and alertness. The main objective is to describe the impact of music on the brain's response to self-referential or neutral stimuli in brain-damaged patients with persistent consciousness disorder after a coma and in healthy participants.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Twenty-four-hour rhythmicities in disorders of consciousness are associated with a favourable outcome.
Gobert F, Corneyllie A, Bastuji H, Berthomier C, et al · · 2023 · cited 5× · PMID 38030756 · DOI 10.1038/s42003-023-05588-2
Verify or expand the search:
- PubMed search for NCT02742506
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT02742506 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Hospices Civils de Lyon
- Last refreshed: 3 September 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02742506.
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