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NCT02742506: MUSICOREVEIL

Beneficial Effects of Music on Cognition and Consciousness Level

Completed NA Last updated 3 September 2025
What this trial tests

NA trial testing Electroencephalography (EEG) in Coma in 86 participants. Completed in 23 October 2019.

Timeline
25 June 2013
Primary endpoint
23 October 2019
23 October 2019

Quick facts

Lead sponsorHospices Civils de Lyon
PhaseNA
StatusCompleted
Study typeINTERVENTIONAL
Allocationnon randomized
Designparallel
Maskingnone
Primary purposeother
Enrollment86
Start date25 June 2013
Primary completion23 October 2019
Estimated completion23 October 2019
Sites1 location across France

Drugs / interventions tested

Conditions studied

Sponsor

Hospices Civils de Lyon — full company profile →

Who can join

Adults 18 to 80, any sex, with Coma. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Exposure to music improves cognitive function in 'healthy' participants and in brain-damaged patients. However, it is still difficult to understand what precisely in music causes a positive effect : are they emotional components, familiarity or preference which improve cognition or is there any specific effect of music? Moreover, it is not yet possible to characterize the neural and functional links between the brain systems solicited by music and those associated with other cognitive functions enhanced by music. Finally, researches on brain-damaged patients have not exploited the potential effect of music on the level of alert and perceptual awareness, while this type of stimulation could be a valuable tool to improve cognition in patients with a disturbance of consciousness and alertness. The main objective is to describe the impact of music on the brain's response to self-referential or neutral stimuli in brain-damaged patients with persistent consciousness disorder after a coma and in healthy participants.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Twenty-four-hour rhythmicities in disorders of consciousness are associated with a favourable outcome.
    Gobert F, Corneyllie A, Bastuji H, Berthomier C, et al · · 2023 · cited 5× · PMID 38030756 · DOI 10.1038/s42003-023-05588-2

Verify or expand the search:

Other trials of Electroencephalography (EEG)

Trials testing the same drug.

Other recruiting trials for Coma

Currently open trials in the same condition.

Other Hospices Civils de Lyon trials

Trials by the same sponsor.

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Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02742506.

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