NCT02739958 is a NA clinical trial of Propofol group in Cancer Larynx, sponsored by Mansoura University.

Who is sponsoring NCT02739958?

NCT02739958 is sponsored by Mansoura University.

What drugs are being tested in NCT02739958?

Interventions in NCT02739958: Propofol group, Isoflurane group.

What condition does NCT02739958 study?

NCT02739958 studies Cancer Larynx, Total Laryngectomy.

Is NCT02739958 still recruiting?

NCT02739958 is currently completed. Last updated 22 September 2020.

Last reviewed 2020-09-22 · How we verify

NCT02739958

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Effects of Propofol-dexmedetomidine on Immune Function in Patients With Cancer Larynx

Completed NA Last updated 22 September 2020

What this trial tests

NA trial testing Propofol group in Cancer Larynx in 40 participants. Completed in 30 October 2016.

Timeline

1 March 2016

Primary endpoint
30 August 2016

30 October 2016

Quick facts

Lead sponsor	Mansoura University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	basic science
Enrollment	40
Start date	1 March 2016
Primary completion	30 August 2016
Estimated completion	30 October 2016
Sites	1 location across Egypt

Drugs / interventions tested

Propofol group
Isoflurane group — full drug profile →

Conditions studied

Cancer Larynx — all drugs for Cancer Larynx →
Total Laryngectomy — all drugs for Total Laryngectomy →

Sponsor

Mansoura University

Who can join

Adults 40 to 85, any sex, with Cancer Larynx or Total Laryngectomy. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The aim of this prospective, randomized clinical study is to compare between propofol and isoflurane on perioperative immune cell populations and function in patients undergoing total laryngectomy surgery.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Trial watch: dexmedetomidine in cancer therapy.
Carnet Le Provost K, Kepp O, Kroemer G, Bezu L. · · 2024 · cited 24× · PMID 38481729 · DOI 10.1080/2162402x.2024.2327143

Verify or expand the search:

Other trials of Propofol group

Trials testing the same drug.

NCT07268872 — Dynamic Effects of Different Anesthetic Agents on the Immune Function of Healthy Volunteers · NA · enrolling by invitation
NCT07116733 — Desflurane vs. Propofol for Cardiac Anesthesia · Phase 3 · recruiting
NCT07192549 — Perioperative GDNF as a Predictive Factor for Postoperative Delirium and Adverse Neurological Outcomes in Pediatric Surg · NA · not yet recruiting
NCT06952608 — Effect of Ciprofol on Intraoperative Hypotension in Elderly Patients Receiving Renin-angiotensin System Inhibitors · Phase 4 · recruiting
NCT06882980 — Comparison of Ciprofol and Propofol Under IoC1 and IoC2 Monitoring for Adenotonsillectomy · NA · recruiting

Other Mansoura University trials

Trials by the same sponsor.

NCT05785377 — Neostigmine as an Adjuvant in Tranversus Abdominis Plane (TAP) Block in Cesarean Section Under Spinal Anesthesia · NA · not yet recruiting
NCT07509567 — Conventional Palatal Crib Versus Bonded Spurs for Anterior Open Bite Treatment · NA · not yet recruiting
NCT07393178 — Efficacy & Safety of High Power vs. Low Power Holmium Laser in Mini-PCNL for Large Renal Stones · NA · not yet recruiting
NCT07436182 — Mitochondrial Redox Modulation in Newly Diagnosed Type 2 Diabetes: A Randomized Controlled Trial Comparing Imeglimin vs. · Phase 4 · not yet recruiting
NCT07534943 — Effectiveness of Oleanolic Acid as Intracanal Medicament on Infectious/Inflammatory Contents in Teeth With Apical Period · NA · active not recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT02739958 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Mansoura University
Last refreshed: 22 September 2020

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02739958.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing