NCT02720315 is a NA clinical trial of Intensive cryotherapy in Pain, sponsored by Stanford University.

Who is sponsoring NCT02720315?

NCT02720315 is sponsored by Stanford University.

What drugs are being tested in NCT02720315?

Interventions in NCT02720315: Intensive cryotherapy.

What condition does NCT02720315 study?

NCT02720315 studies Pain, Opiate, Emergency.

Is NCT02720315 still recruiting?

NCT02720315 is currently completed. Last updated 6 November 2019.

Last reviewed 2019-11-06 · How we verify

NCT02720315

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Intensive Cryotherapy in the Emergency Department for Acute Musculoskeletal Injuries

Completed NA Last updated 6 November 2019

What this trial tests

NA trial testing Intensive cryotherapy in Pain in 38 participants. Completed in 30 October 2019.

Timeline

1 February 2016

Primary endpoint
28 February 2017

30 October 2019

Quick facts

Lead sponsor	Stanford University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	treatment
Enrollment	38
Start date	1 February 2016
Primary completion	28 February 2017
Estimated completion	30 October 2019

Drugs / interventions tested

Intensive cryotherapy

Conditions studied

Pain — all drugs for Pain →
Opiate — all drugs for Opiate →
Emergency — all drugs for Emergency →

Sponsor

Stanford University

Who can join

Adults 18 to 65, any sex, with Pain or Opiate. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Acute musculoskeletal (MSK) injuries, including strains, sprains or contusions, are a common reason patients seek emergency care. Pain control is an essential component of treatment. Within the orthopedic literature, there is robust body of research supporting the use of cryotherapy for post-operative patients and injured athletes. However, within the emergency department (ED), studies have been focused on pharmacologic analgesia. The absence of evidence on optimal method or impact of ice therapy for acute MSK injuries contributes to inconsistent practice patterns that may impede symptom control or increase narcotic usage. The specific aim of the ICED investigation is to evaluate the effectiveness of intensive cryotherapy for the treatment of pain due to acute MSK injuries treated in the ED. Secondary outcomes include length-of-stay (LOS), patient satisfaction, and narcotic usage.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Intensive Cryotherapy in the Emergency Department (ICED): A Randomized Controlled Trial.
Leroux EJ, Kaufman EA, Kontaxis CN, Lipman GS. · · 2021 · cited 3× · PMID 33856337 · DOI 10.5811/westjem.2020.10.48831

Verify or expand the search:

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Other Stanford University trials

Trials by the same sponsor.

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Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT02720315 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Stanford University
Last refreshed: 6 November 2019

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02720315.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing