NCT02703597

Smoking Prevention Through Social Connections Among Adolescents - ASPIRE

Completed NA Results posted Last updated 23 October 2024

What this trial tests

NA trial testing Surveys in Tobacco Use Behavior in 393 participants. Completed in 16 March 2022.

Timeline

1 June 2021

Primary endpoint
16 March 2022

16 March 2022

Quick facts

Lead sponsor	University of Florida
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	prevention
Enrollment	393
Start date	1 June 2021
Primary completion	16 March 2022
Estimated completion	16 March 2022
Sites	1 location across United States

Drugs / interventions tested

• Surveys
• ASPIRE
• GSA-ASPIRE-Network

Conditions studied

• Tobacco Use Behavior — all drugs for Tobacco Use Behavior →

Sponsor

University of Florida

Who can join

Adults 11 to 18, any sex, with Tobacco Use Behavior. Patients with the condition only — healthy volunteers not accepted.

Results — posted to ClinicalTrials.gov

Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.

Susceptibility to Vaping Primary · 4 weeks; Note that each survey completion has a window of 2 weeks, taking into account site availability, presence of students, holidays, and site resources.

During the course of the study surveys reviewed. This outcome was measured using a binary form of the susceptibility to vaping scale, which aims at measuring intention to vape. Scores were 0 (non-susceptible) or 1 (susceptible). A score of 1 has a worse value than a score of 0.

Group	Value	95% CI
ASPIRE Group	66
GSA-ASPIRE-Network Group	118

Susceptibility to Using Conventional Tobacco Primary · 4 weeks; Note that each survey completion has a window of 2 weeks, taking into account site availability, presence of students, holidays, and site resources.

During the course of the study surveys reviewed. This outcome was measured using a binary form of the susceptibility to smoking scale, which aims at measuring intention to use conventional tobacco. Scores were 0 (non-susceptible) or 1 (susceptible). A score of 1 has a worse value than a score of 0. The measure combines susceptibility to using cigarettes, cigars, hookah, and chewing tobacco.

Group	Value	95% CI
ASPIRE Group	63
GSA-ASPIRE-Network Group	106

Sponsor's own description

The central hypothesis of this study is that the addition of social influence strategies to a web-based program called ASPIRE will boost its success in lowering intention to use tobacco among adolescents and experiencing stronger positive social influence. The study will involve a nested group randomized controlled trial with adolescents from after-school programs and schools (e.g., the PK Yonge school) in Florida.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

1. Risk Perception and Knowledge Following a Social Game-Based Tobacco Prevention Program for Adolescents: Pilot Randomized Comparative Trial.
   Khalil G, Ramirez E, Khan M, Zhao B, et al · · 2024 · cited 2× · PMID 39499912 · DOI 10.2196/63296