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NCT02697578

Artificial Intelligence: a New Alternative to Analyse CKD-MBD in Hemodialysis

Completed Last updated 21 December 2018
What this trial tests

trial in Chronic Kidney Disease Mineral and Bone Disorder in 197 participants. Completed in 19 December 2018.

Timeline
1 February 2016
Primary endpoint
19 December 2018
19 December 2018

Quick facts

Lead sponsorMaimónides Biomedical Research Institute of Córdoba
StatusCompleted
Study typeOBSERVATIONAL
Enrollment197
Start date1 February 2016
Primary completion19 December 2018
Estimated completion19 December 2018
Sites1 location across Spain

Conditions studied

Sponsor

Maimónides Biomedical Research Institute of Córdoba

Who can join

Adults 18 to 90, any sex, with Chronic Kidney Disease Mineral and Bone Disorder. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The regulation of calcium, phosphate and parathyroid hormone in hemodialysis is complex and each parameter is not independently regulated. Simultaneous modification in these three parameters are the result of abnormal mineral metabolism and the treatment used. The specific objective of this work is an accurate and exhaustive analysis and description of the complex relationships between clinically relevant parameters in chronic kidney disease metabolism bone disease. In order to achieve these objectives we have used a machine learning approach Random Forest able to extract useful knowledge from a large database. The analysis of the complex interactions between the different parameters needs an advance mathematical approach such as Random Forest . The second aim of this study is to determine whether calcium, phosphate and parathyroid hormone, Fibroblast growth factor 23 and calcitriol are long-term associated with demographic features, mortality, co-morbidity and the therapy prescribed. We will analyze in a prospective study on incident patients, whether the use of this new model may predict the cardiovascular risk..

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Phosphate control in reducing FGF23 levels in hemodialysis patients.
    Rodelo-Haad C, Rodríguez-Ortiz ME, Martin-Malo A, Pendon-Ruiz de Mier MV, et al · · 2018 · cited 26× · PMID 30086150 · DOI 10.1371/journal.pone.0201537

Verify or expand the search:

Other recruiting trials for Chronic Kidney Disease Mineral and Bone Disorder

Currently open trials in the same condition.

Other Maimónides Biomedical Research Institute of Córdoba trials

Trials by the same sponsor.

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