Who is sponsoring NCT02695368?

NCT02695368 is sponsored by Karolinska Institutet.

What drugs are being tested in NCT02695368?

Interventions in NCT02695368: Novaerus NV800 on, Novaerus NV800 off, Novaerus NV800 on or off.

What condition does NCT02695368 study?

NCT02695368 studies Orthopaedic Surgery (30 Minutes or Longer).

Is NCT02695368 still recruiting?

NCT02695368 is currently completed. Last updated 24 June 2022.

Last reviewed 2022-06-24 · How we verify

NCT02695368: EPOS

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

The Effect of Plasma-air-filtration on the Incidence of Surgical Site Infections in Orthopaedic Surgery

Completed NA Last updated 24 June 2022

What this trial tests

NA trial testing Novaerus NV800 on in Orthopaedic Surgery (30 Minutes or Longer) in 45,000 participants. Completed in 31 December 2021.

Timeline

10 April 2017

Primary endpoint
31 December 2021

31 December 2021

Quick facts

Lead sponsor	Karolinska Institutet
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	triple
Primary purpose	prevention
Enrollment	45,000
Start date	10 April 2017
Primary completion	31 December 2021
Estimated completion	31 December 2021
Sites	1 location across Sweden

Drugs / interventions tested

Novaerus NV800 on
Novaerus NV800 off
Novaerus NV800 on or off

Conditions studied

Orthopaedic Surgery (30 Minutes or Longer) — all drugs for Orthopaedic Surgery (30 Minutes or Longer) →

Sponsor

Karolinska Institutet

Who can join

Eligibility, any sex, with Orthopaedic Surgery (30 Minutes or Longer). Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The study is a multicenter, double-blind, randomized, controlled trial conducted at six major university and teaching hospitals with a catchment population of approximately 2 million. In the current study it has been hypothesized that a non-invasive air cleaner utilizing a plasma chamber can significantly reduce the incidence of surgical site infections (SSIs).

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

Gas Plasma Technology-An Asset to Healthcare During Viral Pandemics Such as the COVID-19 Crisis?
Bekeschus S, Kramer A, Suffredini E, von Woedtke T, et al · · 2020 · cited 15× · PMID 34192214 · DOI 10.1109/trpms.2020.3002658
EPOS trial: the effect of air filtration through a plasma chamber on the incidence of surgical site infection in orthopaedic surgery: a study protocol of a randomised, double-blind, placebo-controlled trial.
Persson A, Atroshi I, Tyszkiewicz T, Hailer N, et al · · 2022 · cited 3× · PMID 35115346 · DOI 10.1136/bmjopen-2020-047500
Effect of Plasma Air Purifiers on Infection Rates in Orthopedic Surgery.
Persson A, Atroshi I, Tyszkiewicz T, Hailer NP, et al · · 2025 · PMID 40130977 · DOI 10.1056/evidoa2400289

Verify or expand the search:

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Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT02695368 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Karolinska Institutet
Last refreshed: 24 June 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02695368.

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