NCT02664220 is a Phase 2 clinical trial of Povidone-iodine irrigation in Acute, Perforated Appendicitis, sponsored by The University of Texas Health Science Center, Houston.

Who is sponsoring NCT02664220?

NCT02664220 is sponsored by The University of Texas Health Science Center, Houston.

What drugs are being tested in NCT02664220?

Interventions in NCT02664220: Povidone-iodine irrigation, No irrigation.

What condition does NCT02664220 study?

NCT02664220 studies Acute, Perforated Appendicitis.

Is NCT02664220 still recruiting?

NCT02664220 is currently completed. Last updated 27 March 2019.

Are results published for NCT02664220?

Yes — primary outcome results have been posted to ClinicalTrials.gov. See the outcomes section above for details.

Last reviewed 2019-03-27 · How we verify

NCT02664220

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

A Randomized Pilot Trial of Dilute Povidone-iodine Irrigation vs No Irrigation for Children With Acute, Perforated Appendicitis

Completed Phase 2 Results posted Last updated 27 March 2019

What this trial tests

Phase 2 trial testing Povidone-iodine irrigation in Acute, Perforated Appendicitis in 100 participants. Completed in 1 March 2018.

Timeline

1 April 2016

Primary endpoint
1 March 2018

1 March 2018

Quick facts

Lead sponsor	The University of Texas Health Science Center, Houston
Phase	Phase 2
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	treatment
Enrollment	100
Start date	1 April 2016
Primary completion	1 March 2018
Estimated completion	1 March 2018
Sites	1 location across United States

Drugs / interventions tested

Povidone-iodine irrigation — full drug profile →
No irrigation

Conditions studied

Acute, Perforated Appendicitis — all drugs for Acute, Perforated Appendicitis →

Sponsor

The University of Texas Health Science Center, Houston

Who can join

Adults 2 to 17, any sex, with Acute, Perforated Appendicitis. Patients with the condition only — healthy volunteers not accepted.

What's being measured

Primary outcomes are the specific endpoints the trial is designed to prove or disprove.

Number of Participants With Postoperative Intra-abdominal Abscess
Time frame: 30 days post surgery
30 days postoperative intra-abdominal abscess was confirmed by an image using a standardized definition and protocol

Sponsor's own description

The goal of this study is to compare the efficacy of PVI irrigation to no irrigation for decreasing postoperative intra-abdominal abscesses in children with perforated appendicitis. Additionally, this study aims to verify the safety profile of dilute PVI for intra-abdominal irrigation.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other trials of Povidone-iodine irrigation

Trials testing the same drug.

NCT03447639 — Betadine Bladder Irrigations vs. Standard of Care Prior to Indwelling Catheter Removal · Phase 4 · terminated

Other The University of Texas Health Science Center, Houston trials

Trials by the same sponsor.

NCT04200729 — Povidone-iodine Irrigation for Prevention of Intra-abdominal Abscess in Pediatric Perforated Appendicitis: a Multi-cente · Phase 4 · not yet recruiting
NCT07225062 — Improving HIV Prevention and Substance Use Post-Sexual Assault Services · NA · not yet recruiting
NCT07396974 — Increasing Treatment Access in Trauma Exposed Children: Developing an Adapted Step One Intervention (RCT) · NA · not yet recruiting
NCT07170163 — Navigating the Transition to Adulthood: A Dual Language Mobile App for Latino Youth With ASD and Their Families · NA · not yet recruiting
NCT06915441 — Lipid Infusions to Optimize Nutrition Trial · Phase 2 · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT02664220 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by The University of Texas Health Science Center, Houston
Last refreshed: 27 March 2019

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02664220.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing