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NCT02648191: OBESITE
Preoperative Treatment With Noninvasive Intra-auricular Vagus Nerve Stimulation Pending Bariatric Surgery
NA trial testing NeuroCoach II Stim in Obesity in 27 participants. Terminated before completion.
1 February 2018
Quick facts
| Lead sponsor | Centre Hospitalier Universitaire de Saint Etienne |
|---|---|
| Phase | NA |
| Status | Terminated |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | quadruple |
| Primary purpose | treatment |
| Enrollment | 27 |
| Start date | 2 March 2016 |
| Primary completion | 1 February 2018 |
| Estimated completion | 1 February 2018 |
| Sites | 1 location across France |
Drugs / interventions tested
- NeuroCoach II Stim
- NeuroCoach II Stim
Conditions studied
- Obesity — all drugs for Obesity →
- Bariatric Surgery — all drugs for Bariatric Surgery →
Sponsor
Centre Hospitalier Universitaire de Saint Etienne
Who can join
Adults 18 to 65, any sex, with Obesity or Bariatric Surgery. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Faced with the current obesity epidemic, new avenues of research into effective weight loss must be developed. Among the possible actions on obesity, vagus nerve stimulation has been shown in several studies to be effective in treating epilepsy or depression, at the same time inducing weight loss in those patients. Vagus nerve stimulation has also shown to be effective on weight loss in experimental animal studies. Vagus nerve stimulation has never been attempted in obese patients awaiting bariatric surgery.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Vagus Nerve Stimulation at the Interface of Brain-Gut Interactions.
Bonaz B, Sinniger V, Pellissier S. · · 2019 · cited 83× · PMID 30201788 · DOI 10.1101/cshperspect.a034199
Verify or expand the search:
- PubMed search for NCT02648191
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other Centre Hospitalier Universitaire de Saint Etienne trials
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT02648191 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Centre Hospitalier Universitaire de Saint Etienne
- Last refreshed: 19 July 2018
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02648191.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing