NCT02593903 is a NA clinical trial of Septra in Hypospadias, sponsored by Medical College of Wisconsin.

Who is sponsoring NCT02593903?

NCT02593903 is sponsored by Medical College of Wisconsin.

What drugs are being tested in NCT02593903?

Interventions in NCT02593903: Septra.

What condition does NCT02593903 study?

NCT02593903 studies Hypospadias.

Is NCT02593903 still recruiting?

NCT02593903 is currently completed. Last updated 2 November 2018.

Are results published for NCT02593903?

Yes — primary outcome results have been posted to ClinicalTrials.gov. See the outcomes section above for details.

Last reviewed 2018-11-02 · How we verify

NCT02593903

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Prophylactic Antibiotics Following Distal/Mid-shaft Hypospadias Repair: Are They Necessary?

Completed NA Results posted Last updated 2 November 2018

What this trial tests

NA trial testing Septra in Hypospadias in 67 participants. Completed in 1 April 2018.

Timeline

4 March 2014

Primary endpoint
30 June 2017

1 April 2018

Quick facts

Lead sponsor	Medical College of Wisconsin
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	treatment
Enrollment	67
Start date	4 March 2014
Primary completion	30 June 2017
Estimated completion	1 April 2018
Sites	1 location across United States

Drugs / interventions tested

Septra — full drug profile →

Conditions studied

Hypospadias — all drugs for Hypospadias →

Sponsor

Medical College of Wisconsin

Who can join

Adults 6 Months to 2, male only, with Hypospadias. Patients with the condition only — healthy volunteers not accepted.

What's being measured

Primary outcomes are the specific endpoints the trial is designed to prove or disprove.

Number of Participants With Urinary Tract Infection
Time frame: 4-8 days post-operation
Urinary tract infection (UTI) will be diagnosed based on urine culture positive at 50,000CFUs per mL with one or both of the following: fever \>38 Celsius, or significant fussiness and irritability with voiding per parent report. Asymptomatic bacteriuria is known and expected in this population; therefore culture positive results alone will not be sufficient to meet the definition of UTI.

Sponsor's own description

The purpose of this study is to evaluate the efficacy of prophylactic antibiotics following distal or mid-shaft hypospadias repair in influencing the rate of postoperative urinary tract infection and complications.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Antibiotic Prophylaxis with Trimethoprim-Sulfamethoxazole versus No Treatment after Mid-to-Distal Hypospadias Repair: A Prospective, Randomized Study.
Roth EB, Kryger JV, Durkee CT, Lingongo MA, et al · · 2018 · cited 11× · PMID 29780414 · DOI 10.1155/2018/7031906

Verify or expand the search:

Other recruiting trials for Hypospadias

Currently open trials in the same condition.

NCT07426731 — Comparison of Sacral ESP Block and Dorsal Penile Nerve Block in Pediatric Hypospadias Surgery · NA · recruiting
NCT07319780 — Fibrin-Enhanced TIP Versus Grafted TIP Urethroplasty in Distal Hypospadias · NA · recruiting
NCT07017842 — PREDICT-H Study: Prospective Research on Essential Determinants Influencing Complication Trends in Hypospadias - a Landm · recruiting
NCT06832280 — Improving Parental Support in Hypospadias Care · NA · recruiting
NCT06520423 — Effectiveness of Urethral Stent Irrigation in Preventing Surgical Site Infections in Adolescents With Hypospadias · NA · active not recruiting

Other Medical College of Wisconsin trials

Trials by the same sponsor.

NCT07260552 — Rapid Engagement for Solutions to Population and Outcomes Through Networked Dialogue for Coronary Heart Disease · not yet recruiting
NCT06795360 — Weight Changes After Incretin-mimetics · NA · not yet recruiting
NCT07228208 — Role of Endothelial Dysfunction on Exercise Pressor Reflex in Type 2 Diabetes · NA · not yet recruiting
NCT07298460 — Stimulation-based Therapy to Improve Balance in DCM · Phase 1, PHASE2 · not yet recruiting
NCT07434544 — Cardiometabolic Effects of Non-Nutritive Sweeteners (NNS) in Type 1 Diabetes (T1D) · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT02593903 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Medical College of Wisconsin
Last refreshed: 2 November 2018

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02593903.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing