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NCT02589353
Human Oral Detection of Glucose Olygomers
Phase 4 trial testing Acarbose in Healthy Volunteers in 157 participants. Completed in 16 February 2023.
16 December 2022
Quick facts
| Lead sponsor | Oregon State University |
|---|---|
| Phase | Phase 4 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | basic science |
| Enrollment | 157 |
| Start date | 21 April 2017 |
| Primary completion | 16 December 2022 |
| Estimated completion | 16 February 2023 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Acarbose (ACARBOSE) — full drug profile →
Conditions studied
- Healthy Volunteers — all drugs for Healthy Volunteers →
Sponsor
Oregon State University
Who can join
Adults 18 to 60, any sex, with Healthy Volunteers. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Although salivary contents play a major role in the early stage of food digestion process, their role in taste perception of glucose polymers is essentially unknown. It is hypothesized that the differences in salivary contents, more specifically salivary amylase concentration and activity, influence taste perception of glucose polymers and ultimately eating behavior, which is related to risks in various diseases. The current project will investigate the variation in salivary contents across individuals and its role in taste perception of glucose polymers.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Human taste detection of glucose oligomers with low degree of polymerization.
Pullicin AJ, Penner MH, Lim J. · · 2017 · cited 33× · PMID 28850567 · DOI 10.1371/journal.pone.0183008
Verify or expand the search:
- PubMed search for NCT02589353
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Acarbose
Trials testing the same drug.
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- NCT05629806 — Effect of Acarbose and Mixture of Pioglitazone and Metformin in Patients With Type 2 Diabetes · Phase 3 · unknown
- NCT04180813 — Real-world Study Comparing the Adherence and Effectiveness of Linagliptin vs. Acarbose · terminated
- NCT03794336 — Efficacy and Safety of Alogliptin vs. Acarbose in Chinese Type 2 Diabetes Mellitus (T2DM) Patients With High CV Risk or · Phase 4 · completed
- NCT03602638 — Effects of a Dipeptidyl Peptidase-4 Inhibitor Sitagliptininsulin on the Progression of Coronary Atherosclerosis in Patie · Phase 4 · unknown
Other recruiting trials for Healthy Volunteers
Currently open trials in the same condition.
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- NCT07342114 — A Dose-Escalation Study of RO7875913 in Healthy Participants · Phase 1 · recruiting
Other Oregon State University trials
Trials by the same sponsor.
- NCT06384742 — Shift Worker Intervention for Sleep Health · NA · recruiting
- NCT05965609 — Optimizing Sleep Health in Nurses · NA · completed
- NCT05950672 — Development and Evaluation CAT and Youth · NA · completed
- NCT05482464 — Effect of Daily Consumption of Glycomacropeptide on Gut Microbiome and Blood Functional Proteome of Subjects With Irrita · NA · completed
- NCT06915129 — The Effect of Galactooligosaccharides (GOS) on the Gut Microbiota of Lactose Intolerance Individuals · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT02589353 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Oregon State University
- Last refreshed: 21 February 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02589353.
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