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NCT02567045

Uptake to Colorectal Cancer Screening in Familial-risk Population

Completed NA Last updated 10 August 2020
What this trial tests

NA trial testing annual FIT and colonoscopy in case of a positive test in Colorectal Cancer in 260 participants. Completed in 24 March 2020.

Timeline
25 February 2016
Primary endpoint
31 December 2019
24 March 2020

Quick facts

Lead sponsorHospital Universitario de Canarias
PhaseNA
StatusCompleted
Study typeINTERVENTIONAL
Allocationrandomized
Designparallel
Maskingnone
Primary purposescreening
Enrollment260
Start date25 February 2016
Primary completion31 December 2019
Estimated completion24 March 2020
Sites7 locations across Spain

Drugs / interventions tested

Conditions studied

Sponsor

Hospital Universitario de Canarias

Who can join

Adults 18 to 40, any sex, with Colorectal Cancer or Screening Uptake of Colonoscopy and FIT. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This is a multicenter, controlled, randomized phase III study to compare participation rate with two screening rounds of fecal occult blood test (FIT) versus one-time screening colonoscopy in first degree relatives (FDR) of patients diagnosed of colorectal cancer (CRC). The hypothesis of the study is that annual FIT uptake and colonoscopy when a positive test is higher than that of straightforward colonoscopy. Assuming an uptake of 0.50 for colonoscopy and 0.60 for FIT, a Type I error (alpha) of 5% and a power of 90%, 538 FDRs will be necessary to include in each group.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Screening uptake of colonoscopy versus fecal immunochemical testing in first-degree relatives of patients with non-syndromic colorectal cancer: A multicenter, open-label, parallel-group, randomized trial (ParCoFit study).
    González-López N, Quintero E, Gimeno-Garcia AZ, Bujanda L, et al · · 2023 · cited 6× · PMID 37874831 · DOI 10.1371/journal.pmed.1004298

Verify or expand the search:

Other recruiting trials for Colorectal Cancer

Currently open trials in the same condition.

Other Hospital Universitario de Canarias trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

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