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NCT02559297
Effects of Sevoflurane and Desflurane on Treg
Phase 2 trial testing Sevoflurane in Transplant; Failure, Kidney in 40 participants. Completed in 3 June 2017.
3 June 2017
Quick facts
| Lead sponsor | Mahidol University |
|---|---|
| Phase | Phase 2 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 40 |
| Start date | 10 August 2015 |
| Primary completion | 3 June 2017 |
| Estimated completion | 3 June 2017 |
| Sites | 1 location across Thailand |
Drugs / interventions tested
- Sevoflurane — full drug profile →
- Desflurane (DESFLURANE) — full drug profile →
Conditions studied
- Transplant; Failure, Kidney — all drugs for Transplant; Failure, Kidney →
Sponsor
Mahidol University
Who can join
18 and older, any sex, with Transplant; Failure, Kidney. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This prospective interventional study aims to compare sevoflurane and desflurane anesthetic agents on regulatory T cell (Treg) numbers and its cytokine production in patients undergoing Living Donor Kidney Transplant (LDKT).
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Effects of Desflurane and Sevoflurane anesthesia on regulatory T cells in patients undergoing living donor kidney transplantation: a randomized intervention trial.
Chutipongtanate A, Prukviwat S, Pongsakul N, Srisala S, et al · · 2020 · cited 5× · PMID 32854613 · DOI 10.1186/s12871-020-01130-7 -
Effects of Desflurane and Sevoflurane Anesthesia on Regulatory T Cells in Patients Undergoing Living Donor Kidney Transplantation A Randomized Intervention Trial
Chutipongtanate A, Prukviwat S, Pongsakul N, Sris S, et al · · 2020 · DOI 10.21203/rs.3.rs-37106/v2
Verify or expand the search:
- PubMed search for NCT02559297
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Sevoflurane
Trials testing the same drug.
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- NCT07511634 — Comparison of Sevoflurane and Desflurane on ANI in Patients Undergoing General Anesthesia: a Prospective Randomized Cont · NA · not yet recruiting
- NCT07440758 — Low-Flow Sevoflurane and Desflurane Anesthesia in Laparoscopic Cholecystectomy · NA · not yet recruiting
- NCT07295158 — Effect of Sevoflurane vs Desflurane on Mechanical Power in Laparoscopic Cholecystectomy · NA · recruiting
- NCT07152912 — Impact of Isoflurane and Sevoflurane on Oxidative Stress in Patients Undergoing Laparoscopic Cholecystectomy · NA · recruiting
Other Mahidol University trials
Trials by the same sponsor.
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- NCT07378501 — Thai Version of the Pediatric Quality of Recovery Score (PedSQoR): Translation and Psychometric Validation Study · not yet recruiting
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT02559297 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Mahidol University
- Last refreshed: 15 June 2017
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02559297.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing