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NCT02559297

Effects of Sevoflurane and Desflurane on Treg

Completed Phase 2 Last updated 15 June 2017
What this trial tests

Phase 2 trial testing Sevoflurane in Transplant; Failure, Kidney in 40 participants. Completed in 3 June 2017.

Timeline
10 August 2015
Primary endpoint
3 June 2017
3 June 2017

Quick facts

Lead sponsorMahidol University
PhasePhase 2
StatusCompleted
Study typeINTERVENTIONAL
Allocationrandomized
Designparallel
Maskingdouble
Primary purposetreatment
Enrollment40
Start date10 August 2015
Primary completion3 June 2017
Estimated completion3 June 2017
Sites1 location across Thailand

Drugs / interventions tested

Conditions studied

Sponsor

Mahidol University

Who can join

18 and older, any sex, with Transplant; Failure, Kidney. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This prospective interventional study aims to compare sevoflurane and desflurane anesthetic agents on regulatory T cell (Treg) numbers and its cytokine production in patients undergoing Living Donor Kidney Transplant (LDKT).

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

  1. Effects of Desflurane and Sevoflurane anesthesia on regulatory T cells in patients undergoing living donor kidney transplantation: a randomized intervention trial.
    Chutipongtanate A, Prukviwat S, Pongsakul N, Srisala S, et al · · 2020 · cited 5× · PMID 32854613 · DOI 10.1186/s12871-020-01130-7
  2. Effects of Desflurane and Sevoflurane Anesthesia on Regulatory T Cells in Patients Undergoing Living Donor Kidney Transplantation A Randomized Intervention Trial
    Chutipongtanate A, Prukviwat S, Pongsakul N, Sris S, et al · · 2020 · DOI 10.21203/rs.3.rs-37106/v2

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Other trials of Sevoflurane

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Other Mahidol University trials

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