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NCT02539329

Characterization of Anti-FGFR3 Antibodies

Completed Last updated 10 February 2023
What this trial tests

trial testing Neurological assessment and Blood sample in Sensory Peripheral Neuropathy in 251 participants. Completed in 17 January 2022.

Timeline
3 February 2015
Primary endpoint
15 November 2021
17 January 2022

Quick facts

Lead sponsorCentre Hospitalier Universitaire de Saint Etienne
StatusCompleted
Study typeOBSERVATIONAL
Enrollment251
Start date3 February 2015
Primary completion15 November 2021
Estimated completion17 January 2022
Sites17 locations across France

Drugs / interventions tested

Conditions studied

Sponsor

Centre Hospitalier Universitaire de Saint Etienne

Who can join

18 and older, any sex, with Sensory Peripheral Neuropathy. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Sensory neuronopathies affect sensory neuron in the posterior spinal ganglion. They are responsible for pain, balance disorder (ataxia) and the use of hands. They depend on multiple etiologies. In a retrospective study, the investigators showed that the anti-FGFR3 antibody is a diagnostic marker of a subset of sensory neuronopathies. The investigators believe that other antibodies can be discovered in patients who remain seronegative changing. However, the study is retrospective and only a small number of patients could be identified. Several points therefore need to be clarified or confirmed in a second prospective study.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

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Trials by the same sponsor.

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