NCT02525510 is a NA clinical trial of Pump Eligible - Normothermia - Pump Both Kidneys in Brain Death, sponsored by University of California, San Francisco.

Who is sponsoring NCT02525510?

NCT02525510 is sponsored by University of California, San Francisco.

What drugs are being tested in NCT02525510?

Interventions in NCT02525510: Pump Eligible - Normothermia - Pump Both Kidneys, Pump Eligible - Hypothermia and Pump Right Kidney, Pump Eligible - Hypothermia and Pump Left Kidney, Not Pump Eligible - Normothermia, Not Pump Eligible - Hypothermia.

What condition does NCT02525510 study?

NCT02525510 studies Brain Death, Organ Donation, Organ Transplant Failure or Rejection, Delayed Graft Function.

Is NCT02525510 still recruiting?

NCT02525510 is currently completed. Last updated 14 June 2022.

Last reviewed 2022-06-14 · How we verify

NCT02525510

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Deceased Organ Donor Interventions to Protect Kidney Graft Function

Completed NA Last updated 14 June 2022

What this trial tests

NA trial testing Pump Eligible - Normothermia - Pump Both Kidneys in Brain Death in 1,427 participants. Completed in 1 June 2022.

Timeline

26 July 2017

Primary endpoint
1 June 2022

1 June 2022

Quick facts

Lead sponsor	University of California, San Francisco
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	triple
Primary purpose	prevention
Enrollment	1,427
Start date	26 July 2017
Primary completion	1 June 2022
Estimated completion	1 June 2022
Sites	7 locations across United States

Drugs / interventions tested

Pump Eligible - Normothermia - Pump Both Kidneys
Pump Eligible - Hypothermia and Pump Right Kidney
Pump Eligible - Hypothermia and Pump Left Kidney
Not Pump Eligible - Normothermia
Not Pump Eligible - Hypothermia

Conditions studied

Brain Death — all drugs for Brain Death →
Organ Donation — all drugs for Organ Donation →
Organ Transplant Failure or Rejection — all drugs for Organ Transplant Failure or Rejection →
Delayed Graft Function — all drugs for Delayed Graft Function →

Sponsor

University of California, San Francisco

Who can join

18 and older, any sex, with Brain Death or Organ Donation. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

To protect kidney function during the transplantation process by comparing mild hypothermia in the deceased organ donor before organs are recovered and pulsatile perfusion of the kidney after recovery and prior to transplantation.

Publications & conference data

4 peer-reviewed publications reference this trial (live from Europe PMC):

Machine perfusion preservation versus static cold storage for deceased donor kidney transplantation.
Tingle SJ, Figueiredo RS, Moir JA, Goodfellow M, et al · · 2019 · cited 131× · PMID 30875082 · DOI 10.1002/14651858.cd011671.pub2
Hypothermia or Machine Perfusion in Kidney Donors.
Malinoski D, Saunders C, Swain S, Groat T, et al · · 2023 · cited 61× · PMID 36724328 · DOI 10.1056/nejmoa2118265
Medical Therapies to Reduce Delayed Graft Function and Improve Long-Term Graft Survival: Are We Making Progress?
Lim MA, Bloom RD. · · 2020 · cited 21× · PMID 31911413 · DOI 10.2215/cjn.13961119
Therapeutic Hypothermia in Low-Risk Nonpumped Brain-Dead Kidney Donors: A Randomized Clinical Trial.
Patel MS, Salcedo-Betancourt JD, Saunders C, Broglio K, et al · · 2024 · cited 6× · PMID 38416500 · DOI 10.1001/jamanetworkopen.2023.53785

Verify or expand the search:

Other recruiting trials for Brain Death

Currently open trials in the same condition.

NCT06640088 — Determining ICU Staffs Conceptions, Opinions, Views, Experiences and Reflection of Brain Death and Organ Donation · recruiting

Other University of California, San Francisco trials

Trials by the same sponsor.

NCT05284773 — Screening for Acute Malnutrition · NA · withdrawn
NCT04634851 — Video Home Visits for Dietary Counselling · NA · not yet recruiting
NCT06065670 — Assessing Changes in Multi-parametric MRI in Patients With Acute Demyelinating Lesions Taking Clemastine Fumarate as a M · Phase 1, PHASE2 · not yet recruiting
NCT07534098 — Intervention for Hearing Health Among Native Americans · NA · not yet recruiting
NCT06960421 — Exercise-based Frailty Intervention in Lung Transplantation (XFIT) · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT02525510 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of California, San Francisco
Last refreshed: 14 June 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02525510.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing