NCT02443558: CSI:Brainwave

Brainwave Control of a Wearable Robotic Arm for Rehabilitation and Neurophysiological Study in Cervical Spine Injury

Completed NA Last updated 17 February 2020

What this trial tests

NA trial testing Brain-Computer Interface control of robotic arms. in Spinal Cord Injuries in 20 participants. Completed in 31 December 2018.

Timeline

15 December 2016

Primary endpoint
31 December 2018

31 December 2018

Quick facts

Lead sponsor	Aristotle University Of Thessaloniki
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	non randomized
Design	parallel
Masking	none
Primary purpose	basic science
Enrollment	20
Start date	15 December 2016
Primary completion	31 December 2018
Estimated completion	31 December 2018
Sites	1 location across Greece

Drugs / interventions tested

• Brain-Computer Interface control of robotic arms.
• MERCURY v2.0 robotic arms

Conditions studied

• Spinal Cord Injuries — all drugs for Spinal Cord Injuries →

Sponsor

Aristotle University Of Thessaloniki

Who can join

14 and older, any sex, with Spinal Cord Injuries. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

CSI:Brainwave is a multidisciplinary neurophysiological project, developed by the Lab of Medical Physics, School of Medicine, Aristotle University of Thessaloniki and supported by two Neurosurgical Departments. The project officially commenced on April 2014 and the first year was awarded the 2013 Mario Boni Research Grant by the Cervical Spine Research Society-European Section (CSRS-ES). The website for the project can be accessed at http://medphys.med.auth.gr/content/csi-brainwave.

The investigation's primary objectives include the development, testing and optimization of a mountable robotic arm controlled with wireless Brain-Computer Interface, the development and validation of a self-paced neuro-rehabilitation protocol for patients with Cervical Spinal Cord Injury and the study of cortical activity in acute and chronic spinal cord injury.

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

1. A Systematic Review of Investigations into Functional Brain Connectivity Following Spinal Cord Injury.
   Athanasiou A, Klados MA, Pandria N, Foroglou N, et al · · 2017 · cited 29× · PMID 29163098 · DOI 10.3389/fnhum.2017.00517
2. Functional Brain Connectivity during Multiple Motor Imagery Tasks in Spinal Cord Injury.
   Athanasiou A, Terzopoulos N, Pandria N, Xygonakis I, et al · · 2018 · cited 16× · PMID 29853852 · DOI 10.1155/2018/9354207
3. Motor imagery for paediatric neurorehabilitation: how much do we know? Perspectives from a systematic review.
   Gentile AE, Rinella S, Desogus E, Verrelli CM, et al · · 2024 · cited 8× · PMID 38571523 · DOI 10.3389/fnhum.2024.1245707