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NCT02439255
Effect of Black Raspberry Phytochemicals on Oral Microbiome in Current Smokers and Non-smokers
NA trial testing Laboratory Biomarker Analysis in Healthy Subject in 148 participants. Completed in 30 April 2022.
30 June 2018
Quick facts
| Lead sponsor | Ohio State University Comprehensive Cancer Center |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | prevention |
| Enrollment | 148 |
| Start date | 4 December 2015 |
| Primary completion | 30 June 2018 |
| Estimated completion | 30 April 2022 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Laboratory Biomarker Analysis — full drug profile →
- Phytochemical
- Placebo
- Screening Questionnaire Administration
Conditions studied
- Healthy Subject — all drugs for Healthy Subject →
- Tobacco Use Disorder — all drugs for Tobacco Use Disorder →
Sponsor
Ohio State University Comprehensive Cancer Center
Who can join
Adults 18 to 50, any sex, with Healthy Subject or Tobacco Use Disorder. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This randomized clinical trial studies the effects of black raspberry compounds (phytochemicals) on the bacteria in the mouth (oral microbiome) of current smokers and non-smokers. The oral microbiome protects the body from pathogenic bacteria. Smoking alters the oral microbiome and may increase the susceptibility to cancer by modulating normal host-bacteria interactions. Black raspberry phytochemicals may protect the oral microbiome of smokers and may lower their risk of developing oral cancer.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Harnessing Nature's Toolbox: Naturally Derived Bioactive Compounds in Nanotechnology Enhanced Formulations.
Sanjai C, Gaonkar SL, Hakkimane SS. · · 2024 · cited 10× · PMID 39494011 · DOI 10.1021/acsomega.4c07756
Verify or expand the search:
- PubMed search for NCT02439255
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other Ohio State University Comprehensive Cancer Center trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT02439255 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Ohio State University Comprehensive Cancer Center
- Last refreshed: 5 October 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02439255.
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