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NCT02435472: ASX

Active Surveillance Exercise Clinical Trial

Completed NA Last updated 11 April 2025
What this trial tests

NA trial testing Exercise in Localized Prostate Cancer in 104 participants. Completed in 31 December 2024.

Timeline
21 June 2016
Primary endpoint
30 April 2023
31 December 2024

Quick facts

Lead sponsorUniversity of California, San Francisco
PhaseNA
StatusCompleted
Study typeINTERVENTIONAL
Allocationrandomized
Designparallel
Maskingnone
Primary purposesupportive care
Enrollment104
Start date21 June 2016
Primary completion30 April 2023
Estimated completion31 December 2024
Sites1 location across United States

Drugs / interventions tested

Conditions studied

Sponsor

University of California, San Francisco

Who can join

18 and older, male only, with Localized Prostate Cancer or Active Surveillance for Prostate Cancer. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This phase 2, open-label, dual-center, two-arm randomized controlled trial (RCT) investigates the effects of 16 weeks of structured aerobic training, relative to usual care (print material with physical activity guidance). Prostate genomic signatures represent the functional activity of all genes in the genome and are converted into genomic risk scores which correspond to the probability of a progression event (chance of having more aggressive disease). A structured exercise program may alter the genomic risk score and improve prediction of aggressive disease.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

  1. Diet and lifestyle considerations for patients with prostate cancer.
    Zuniga KB, Chan JM, Ryan CJ, Kenfield SA. · · 2020 · cited 36× · PMID 31327752 · DOI 10.1016/j.urolonc.2019.06.018
  2. Feasibility, safety, and acceptability of a remotely monitored exercise pilot CHAMP: A Clinical trial of High-intensity Aerobic and resistance exercise for Metastatic castrate-resistant Prostate cancer.
    Kenfield SA, Van Blarigan EL, Panchal N, Bang A, et al · · 2021 · cited 20× · PMID 34636156 · DOI 10.1002/cam4.4324

Verify or expand the search:

Other trials of Exercise

Trials testing the same drug.

Other recruiting trials for Localized Prostate Cancer

Currently open trials in the same condition.

Other University of California, San Francisco trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02435472.

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