Last reviewed · How we verify
NCT02435472: ASX
Active Surveillance Exercise Clinical Trial
NA trial testing Exercise in Localized Prostate Cancer in 104 participants. Completed in 31 December 2024.
30 April 2023
Quick facts
| Lead sponsor | University of California, San Francisco |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | supportive care |
| Enrollment | 104 |
| Start date | 21 June 2016 |
| Primary completion | 30 April 2023 |
| Estimated completion | 31 December 2024 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Exercise
- Cardiopulmonary Exercise Test (CPET)
Conditions studied
- Localized Prostate Cancer — all drugs for Localized Prostate Cancer →
- Active Surveillance for Prostate Cancer — all drugs for Active Surveillance for Prostate Cancer →
Sponsor
University of California, San Francisco
Who can join
18 and older, male only, with Localized Prostate Cancer or Active Surveillance for Prostate Cancer. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This phase 2, open-label, dual-center, two-arm randomized controlled trial (RCT) investigates the effects of 16 weeks of structured aerobic training, relative to usual care (print material with physical activity guidance). Prostate genomic signatures represent the functional activity of all genes in the genome and are converted into genomic risk scores which correspond to the probability of a progression event (chance of having more aggressive disease). A structured exercise program may alter the genomic risk score and improve prediction of aggressive disease.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Diet and lifestyle considerations for patients with prostate cancer.
Zuniga KB, Chan JM, Ryan CJ, Kenfield SA. · · 2020 · cited 36× · PMID 31327752 · DOI 10.1016/j.urolonc.2019.06.018 -
Feasibility, safety, and acceptability of a remotely monitored exercise pilot CHAMP: A Clinical trial of High-intensity Aerobic and resistance exercise for Metastatic castrate-resistant Prostate cancer.
Kenfield SA, Van Blarigan EL, Panchal N, Bang A, et al · · 2021 · cited 20× · PMID 34636156 · DOI 10.1002/cam4.4324
Verify or expand the search:
- PubMed search for NCT02435472
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Exercise
Trials testing the same drug.
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- NCT07589725 — Mulligan Mobilization in Lateral Elbow Tendinopathy · NA · not yet recruiting
- NCT07524400 — Effects of Physical Exercise Combined With Transcranial Direct Current Stimulation in Parkinson's Disease · NA · recruiting
- NCT06627569 — Exercise Effects on the Neurobiology Underlying Stress-related Eating Behaviors in Veterans · NA · not yet recruiting
Other recruiting trials for Localized Prostate Cancer
Currently open trials in the same condition.
- NCT06966778 — Oxybutynin ER to Promote Early Continence Recovery After Robotic Prostatectomy: A Randomized Controlled Trial · NA · recruiting
- NCT06825091 — Is Adaptive SBRT for Prostate vs Image-guided Radiotherapy a True Evolution (ASPIRE) · Phase 3 · recruiting
- NCT06117059 — The PRECISION Study: 3 Fractions of Prostate SBRT and RayPilot HypoCath Image Guidance · NA · recruiting
- NCT06325774 — Radical Hypofractionated Radiotherapy for Localized Prostate Cancer · NA · recruiting
- NCT06362577 — Clinical Study of HIFU for Localized Prostate Cancer · recruiting
Other University of California, San Francisco trials
Trials by the same sponsor.
- NCT05284773 — Screening for Acute Malnutrition · NA · withdrawn
- NCT04634851 — Video Home Visits for Dietary Counselling · NA · not yet recruiting
- NCT06065670 — Assessing Changes in Multi-parametric MRI in Patients With Acute Demyelinating Lesions Taking Clemastine Fumarate as a M · Phase 1, PHASE2 · not yet recruiting
- NCT07534098 — Intervention for Hearing Health Among Native Americans · NA · not yet recruiting
- NCT06960421 — Exercise-based Frailty Intervention in Lung Transplantation (XFIT) · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT02435472 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of California, San Francisco
- Last refreshed: 11 April 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02435472.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing