NCT02424552 (EVITA) is a Phase 4 clinical trial of Vitamin D3 in Asthma, sponsored by Johannes Gutenberg University Mainz.

Who is sponsoring NCT02424552?

NCT02424552 is sponsored by Johannes Gutenberg University Mainz.

What drugs are being tested in NCT02424552?

Interventions in NCT02424552: Vitamin D3, Placebo.

Is NCT02424552 still recruiting?

NCT02424552 is currently terminated. Last updated 1 May 2017.

Last reviewed 2017-05-01 · How we verify

NCT02424552: EVITA

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Effect of Vitamin D as add-on Therapy for Vitamin D Insufficient Patients With Severe Asthma

Terminated Phase 4 Last updated 1 May 2017

What this trial tests

Phase 4 trial testing Vitamin D3 in Asthma in 54 participants. Terminated before completion.

Timeline

26 June 2015

Primary endpoint
9 February 2017

9 March 2017

Quick facts

Lead sponsor	Johannes Gutenberg University Mainz
Phase	Phase 4
Status	Terminated
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	quadruple
Primary purpose	treatment
Enrollment	54
Start date	26 June 2015
Primary completion	9 February 2017
Estimated completion	9 March 2017
Sites	9 locations across Germany

Drugs / interventions tested

Vitamin D3 (cholecalciferol) — full drug profile →
Placebo

Conditions studied

Asthma — all drugs for Asthma →

Sponsor

Johannes Gutenberg University Mainz

Who can join

18 and older, any sex, with Asthma. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The purpose of the EVITA trial is to compare the effects of vitamin D therapy with placebo on reducing the dose of inhaled or oral corticosteroids in patients with severe asthma and vitamin D insufficiency.

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

Vitamin D supplementation to prevent asthma exacerbations: a systematic review and meta-analysis of individual participant data.
Jolliffe DA, Greenberg L, Hooper RL, Griffiths CJ, et al · · 2017 · cited 210× · PMID 28986128 · DOI 10.1016/s2213-2600(17)30306-5
Vitamin D for the management of asthma.
Martineau AR, Cates CJ, Urashima M, Jensen M, et al · · 2016 · cited 113× · PMID 27595415 · DOI 10.1002/14651858.cd011511.pub2
Vitamin D for the management of asthma.
Williamson A, Martineau AR, Sheikh A, Jolliffe D, et al · · 2023 · cited 28× · PMID 36744416 · DOI 10.1002/14651858.cd011511.pub3

Verify or expand the search:

Other trials of Vitamin D3

Trials testing the same drug.

NCT06201013 — Vitamin D Treat-to-Target Strategy for Children With Overactive Bladder-Wet · NA · recruiting
NCT07460336 — Effects of Cofrogliptin on Beta-Cell Function in LADA Patients · NA · not yet recruiting
NCT07006714 — Preoperative Correction of Vitamin D Deficiency in Total Joint Arthroplasty (TJA) · Phase 4 · active not recruiting
NCT07269223 — Oral Vitamin D3 Effect on Inflammatory Biomarkers in Ulcerative Colitis Patients · NA · recruiting
NCT07048860 — ICOPE INTENSE-K Pilot Study · NA · recruiting

Other recruiting trials for Asthma

Currently open trials in the same condition.

NCT07525375 — A Phase II Study to Investigate Lung Function With 2 Different Doses of Inhaled Glycopyrronium Taken With BFF Compared t · Phase 2 · recruiting
NCT07536256 — Community Connections Through Native Hawaiian Cultural Values to Strengthen Youth Resilience, Health, and Well-Being · NA · recruiting
NCT07556159 — A Study Evaluating Disease Characteristics and Outcomes in Participants With Asthma in Routine Clinical Practice · recruiting
NCT07282886 — VENTURI (VENTilation Using Respiratory Imaging) · Phase 2 · recruiting
NCT07433569 — A Study to Investigate How Budesonide and Formoterol Move Through the Body (Pharmacokinetics) When Delivered With Differ · Phase 1 · recruiting

Other Johannes Gutenberg University Mainz trials

Trials by the same sponsor.

NCT06269874 — Study Comparing Two Administration Pathways for Adenosine During Microvascular Function Assessment · NA · not yet recruiting
NCT07076511 — A Novel Intuitive Airway Trolley for Quick Decision-making in Simulated Unexpected Difficult Airway Situations: Evaluati · NA · completed
NCT06739993 — Effects of Autonomic Nervous System Modulation by Heart Rate Variability Biofeedback Training With Resonant Frequency Br · NA · recruiting
NCT06514495 — Differential Effects of in Vivo and Virtual Exposure Therapy in Agoraphobia · NA · recruiting
NCT07460791 — Alcon Hydrus Stent Implantation - Long Term Follow up After 8 Years · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT02424552 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Johannes Gutenberg University Mainz
Last refreshed: 1 May 2017

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02424552.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing