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NCT02399384

Pericardial Fat and Inflammation in HIV Patients and Controls

Completed Last updated 18 January 2020
What this trial tests

trial in Coronary Artery Disease in 12 participants. Completed in 1 July 2018.

Timeline
14 January 2015
Primary endpoint
1 July 2018
1 July 2018

Quick facts

Lead sponsorUniversity of Cincinnati
StatusCompleted
Study typeOBSERVATIONAL
Enrollment12
Start date14 January 2015
Primary completion1 July 2018
Estimated completion1 July 2018
Sites1 location across United States

Conditions studied

Sponsor

University of Cincinnati

Who can join

18 and older, any sex, with Coronary Artery Disease or Human Immunodeficiency Virus (HIV). Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The investigators propose to correlate 1) cardiac MRI pericardial adipose volume, 2) the presence of pericardial monocytes and 3) circulating immune biomarkers in persons with and without CHD and HIV infection compared to seronegative controls with known CHD. The investigators aim to test the hypothesis that higher amounts of pericardial fat deposition and increased presence of monocytes within this adipose tissue are associated with underlying coronary artery disease in persons with HIV infection as measured by cardiac MRI.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. What happens to cardiovascular system behind the undetectable level of HIV viremia?
    d'Ettorre G, Ceccarelli G, Pavone P, Vittozzi P, et al · · 2016 · cited 27× · PMID 27127532 · DOI 10.1186/s12981-016-0105-z

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Other recruiting trials for Coronary Artery Disease

Currently open trials in the same condition.

Other University of Cincinnati trials

Trials by the same sponsor.

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Data sources for this page

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