NCT02356848 (STEP UP) is a NA clinical trial of Tailored Intervention (TI) in Diabetes, sponsored by VA Office of Research and Development.

Who is sponsoring NCT02356848?

NCT02356848 is sponsored by VA Office of Research and Development.

What drugs are being tested in NCT02356848?

Interventions in NCT02356848: Tailored Intervention (TI), Current Practice (CP).

What condition does NCT02356848 study?

NCT02356848 studies Diabetes, Foot Ulcer.

Is NCT02356848 still recruiting?

NCT02356848 is currently completed. Last updated 8 October 2021.

Last reviewed 2021-10-08 · How we verify

NCT02356848: STEP UP

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

STEP UP to Avert Amputation in Diabetes

Completed NA Last updated 8 October 2021

What this trial tests

NA trial testing Tailored Intervention (TI) in Diabetes in 241 participants. Completed in 30 September 2021.

Timeline

3 September 2015

Primary endpoint
30 June 2021

30 September 2021

Quick facts

Lead sponsor	VA Office of Research and Development
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	prevention
Enrollment	241
Start date	3 September 2015
Primary completion	30 June 2021
Estimated completion	30 September 2021
Sites	1 location across United States

Drugs / interventions tested

Tailored Intervention (TI)
Current Practice (CP)

Conditions studied

Diabetes — all drugs for Diabetes →
Foot Ulcer — all drugs for Foot Ulcer →

Sponsor

VA Office of Research and Development — full company profile →

Who can join

21 and older, any sex, with Diabetes or Foot Ulcer. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This study will evaluate a comprehensive tailored behavioral intervention aimed to improve foot self-care and self-monitoring (combined with dermal thermometry) to prevent recurrent ulcers in Veterans at highest risk of amputation. This intervention may be a novel strategy for improving self-care and early detection of foot abnormalities in this at-risk population using psychological theories to target multiple health behaviors simultaneously. This could be an efficient and cost-effective approach to improve diabetes-related foot health behavior, and other risk factors in patients who are vulnerable to devastating consequences related to amputation.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Navigating COVID-19 and related challenges to completing clinical trials: Lessons from the PATRIOT and STEP-UP randomized prevention trials.
Salovaara PK, Li C, Nicholson A, Lipsitz SR, et al · · 2023 · cited 1× · PMID 36562090 · DOI 10.1177/17407745221140041

Verify or expand the search:

Other recruiting trials for Diabetes

Currently open trials in the same condition.

NCT07272837 — Impact of Semaglutide (Ozempic/Wegovy®) on Heart and Muscle Mass · recruiting
NCT07479134 — Production of Stem Cells for the Generation of Pancreatic Cells · NA · recruiting
NCT07441655 — Families Implementing Good Health Traditions for Life · NA · recruiting
NCT06724172 — CHIME: Comparing Health Interventions for Maternal Equity · NA · recruiting
NCT07417865 — ECHO Diabetes FQHC · recruiting

Other VA Office of Research and Development trials

Trials by the same sponsor.

NCT07456150 — Personalizing Veteran Pain Care: Adapting Coaching Interventions to Support Maintenance of Self-Care · Phase 1 · not yet recruiting
NCT06746727 — The Development of a Transdiagnostic Intervention to Improve Social Functioning and Intimate Relationships Among Veteran · NA · not yet recruiting
NCT07362576 — Perinatal Peer Support for Veterans With Serious Mental Illness · NA · not yet recruiting
NCT06766331 — Integrated Care Versus Usual Care for Opioid Use Disorder and Infectious Diseases in Veterans · NA · not yet recruiting
NCT07397195 — ACT for Veterans With IBD and Mental Health Challenges · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT02356848 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by VA Office of Research and Development
Last refreshed: 8 October 2021

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02356848.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing