NCT02291952 is a NA clinical trial of Meal schedule in Circadian Dysregulation, sponsored by Brigham and Women's Hospital.

Who is sponsoring NCT02291952?

NCT02291952 is sponsored by Brigham and Women's Hospital.

What drugs are being tested in NCT02291952?

Interventions in NCT02291952: Meal schedule.

What condition does NCT02291952 study?

NCT02291952 studies Circadian Dysregulation.

Is NCT02291952 still recruiting?

NCT02291952 is currently completed. Last updated 19 March 2020.

Last reviewed 2020-03-19 · How we verify

NCT02291952

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Development of Countermeasures Against Adverse Metabolic Effects of Shift Work

Completed NA Last updated 19 March 2020

What this trial tests

NA trial testing Meal schedule in Circadian Dysregulation in 20 participants. Completed in 29 August 2018.

Timeline

19 March 2015

Primary endpoint
29 August 2018

29 August 2018

Quick facts

Lead sponsor	Brigham and Women's Hospital
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	basic science
Enrollment	20
Start date	19 March 2015
Primary completion	29 August 2018
Estimated completion	29 August 2018
Sites	1 location across United States

Drugs / interventions tested

Meal schedule

Conditions studied

Circadian Dysregulation — all drugs for Circadian Dysregulation →

Sponsor

Brigham and Women's Hospital

Who can join

Adults 18 to 35, any sex, with Circadian Dysregulation. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The goal of this application is to determine whether changing the timing of food intake prevents the adverse metabolic effects of circadian misalignment.

Publications & conference data

4 peer-reviewed publications reference this trial (live from Europe PMC):

Daytime eating prevents internal circadian misalignment and glucose intolerance in night work.
Chellappa SL, Qian J, Vujovic N, Morris CJ, et al · · 2021 · cited 86× · PMID 34860550 · DOI 10.1126/sciadv.abg9910
Proof-of-principle demonstration of endogenous circadian system and circadian misalignment effects on human oral microbiota.
Chellappa SL, Engen PA, Naqib A, Qian J, et al · · 2022 · cited 19× · PMID 34861073 · DOI 10.1096/fj.202101153r
Daytime eating during simulated night work mitigates changes in cardiovascular risk factors: secondary analyses of a randomized controlled trial.
Chellappa SL, Gao L, Qian J, Vujovic N, et al · · 2025 · cited 11× · PMID 40199860 · DOI 10.1038/s41467-025-57846-y
Endogenous circadian rhythms in mood and well-being.
Scheer FAJL, Chellappa SL. · · 2024 · cited 10× · PMID 37648646 · DOI 10.1016/j.sleh.2023.07.012

Verify or expand the search:

Other recruiting trials for Circadian Dysregulation

Currently open trials in the same condition.

NCT07329283 — Nighttime Synchrony of Your Nutrition and Circadian Health · NA · recruiting
NCT07203196 — Circadian Health Regulation and Optimization for Rejuvenation Outcomes · NA · active not recruiting
NCT06922409 — The Effects of Naturalistic Light on Post Stroke Complications Related Brain Areas in Stroke Patients During Admission f · NA · recruiting
NCT05986604 — NIA_Improving Function and Well-being by Improving Patient Memory: Transdiagnostic Sleep and Circadian Treatment · NA · recruiting
NCT05167695 — Maintaining Behavior Change: An Evaluation of a Habit-based Sleep Health Intervention · NA · active not recruiting

Other Brigham and Women's Hospital trials

Trials by the same sponsor.

NCT07011758 — Dynamic Treatment Regimes for Opioid Use Disorder · Phase 2 · not yet recruiting
NCT06310018 — Augmented Ultrasound-Facilitated, Catheter-Directed Fibrinolysis for PE · suspended
NCT04519177 — Randomized Trial of a Sleep Disorders Program on Firefighter Safety and Disability ... · NA · not yet recruiting
NCT06355986 — Computerized Decision Support to Prevent Stroke in Atrial Fibrillation · NA · not yet recruiting
NCT06099275 — Evaluation of Hemodynamics in People With Untreated Preeclampsia Using Echocardiography · suspended

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT02291952 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Brigham and Women's Hospital
Last refreshed: 19 March 2020

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02291952.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing