Last reviewed · How we verify
NCT05986604
NIA_Improving Function and Well-being by Improving Patient Memory: Transdiagnostic Sleep and Circadian Treatment
NA trial testing Memory Support Intervention in Sleep Disorder in 178 participants. Currently enrolling.
28 February 2028
Quick facts
| Lead sponsor | University of California, Berkeley |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | triple |
| Primary purpose | treatment |
| Enrollment | 178 |
| Start date | 4 January 2024 |
| Primary completion | 28 February 2028 |
| Estimated completion | 28 July 2028 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Memory Support Intervention
- Transdiagnostic Intervention for Sleep and Circadian Dysfunction
Conditions studied
- Sleep Disorder — all drugs for Sleep Disorder →
- Circadian Dysregulation — all drugs for Circadian Dysregulation →
- Memory Impairment — all drugs for Memory Impairment →
Sponsor
University of California, Berkeley
Who can join
50 and older, any sex, with Sleep Disorder or Circadian Dysregulation. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Mental illness is often chronic, severe, and difficult to treat. Though there has been significant progress towards establishing effective and efficient interventions for psychological health problems, many individuals do not gain lasting benefits from these treatments. The Memory Support Intervention (MSI) was developed utilizing existing findings from the cognitive science literature to improve treatment outcomes. In this study, the investigators aim to conduct an open trial that includes individuals 50 years and older to assess if a novel version of the Memory Support Intervention improves sleep and circadian functioning, reduces functional impairment, and improves patient memory for treatment.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Integrating the Memory Support Intervention into the Transdiagnostic Intervention for Sleep and Circadian Dysfunction (TranS-C): can improving memory for treatment in midlife and older adults improve patient outcomes? Study protocol for a randomized controlled trial.
Milner AE, Hache RE, Oliver S, Sarfan LD, et al · · 2024 · cited 2× · PMID 39363383 · DOI 10.1186/s13063-024-08468-0
Verify or expand the search:
- PubMed search for NCT05986604
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other University of California, Berkeley trials
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05986604 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of California, Berkeley
- Last refreshed: 24 November 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05986604.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing