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NCT02287129: MEMORI

Evaluation for the Individualization of Therapy in Adenocarcinomas of the Gastroesophageal Junction

Completed Phase 2 Last updated 28 November 2023
What this trial tests

Phase 2 trial testing Oxaliplatin in Adenocarcinoma of the Esophagogastric Junction in 75 participants. Completed in 7 August 2020.

Timeline
5 December 2014
Primary endpoint
7 August 2020
7 August 2020

Quick facts

Lead sponsorTechnical University of Munich
PhasePhase 2
StatusCompleted
Study typeINTERVENTIONAL
Allocationnon randomized
Designparallel
Maskingnone
Primary purposetreatment
Enrollment75
Start date5 December 2014
Primary completion7 August 2020
Estimated completion7 August 2020
Sites1 location across Germany

Drugs / interventions tested

Conditions studied

Sponsor

Technical University of Munich

Who can join

18 and older, any sex, with Adenocarcinoma of the Esophagogastric Junction. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Metabolic and Molecular Response evaluation for the individualization of therapy in adenocarcinomas of the gastroesophageal junction by evaluation of the R0 resection rate for patients with metabolically (ie, according to PET criteria) chemotherapy-resistant locally advanced AEG, who receive an intensified neoadjuvant chemoradiotherapy (INRCT). Additonal efforts will be done by investigation of molecular and metabolic biomarkers in relation to their predictive and prognostic value by correlating them with histopathologic responses and clinical outcome in an exploratory approach.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

  1. Trial Watch: Immunogenic cell death inducers for anticancer chemotherapy.
    Pol J, Vacchelli E, Aranda F, Castoldi F, et al · · 2015 · cited 238× · PMID 26137404 · DOI 10.1080/2162402x.2015.1008866
  2. UEG Week 2021 Oral Presentations
    · 2021

Verify or expand the search:

Other trials of Oxaliplatin

Trials testing the same drug.

Other recruiting trials for Adenocarcinoma of the Esophagogastric Junction

Currently open trials in the same condition.

Other Technical University of Munich trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02287129.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing