Last reviewed · How we verify
NCT02287129: MEMORI
Evaluation for the Individualization of Therapy in Adenocarcinomas of the Gastroesophageal Junction
Phase 2 trial testing Oxaliplatin in Adenocarcinoma of the Esophagogastric Junction in 75 participants. Completed in 7 August 2020.
7 August 2020
Quick facts
| Lead sponsor | Technical University of Munich |
|---|---|
| Phase | Phase 2 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | non randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 75 |
| Start date | 5 December 2014 |
| Primary completion | 7 August 2020 |
| Estimated completion | 7 August 2020 |
| Sites | 1 location across Germany |
Drugs / interventions tested
- Oxaliplatin (Oxaliplatin) — full drug profile →
- Epirubicin (EPIRUBICIN) — full drug profile →
- Capecitabine (capecitabine) — full drug profile →
- 5-FU
- Carboplatin
- Paclitaxel — full drug profile →
- radiation
- Biopsy
Conditions studied
- Adenocarcinoma of the Esophagogastric Junction — all drugs for Adenocarcinoma of the Esophagogastric Junction →
Sponsor
Technical University of Munich
Who can join
18 and older, any sex, with Adenocarcinoma of the Esophagogastric Junction. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Metabolic and Molecular Response evaluation for the individualization of therapy in adenocarcinomas of the gastroesophageal junction by evaluation of the R0 resection rate for patients with metabolically (ie, according to PET criteria) chemotherapy-resistant locally advanced AEG, who receive an intensified neoadjuvant chemoradiotherapy (INRCT). Additonal efforts will be done by investigation of molecular and metabolic biomarkers in relation to their predictive and prognostic value by correlating them with histopathologic responses and clinical outcome in an exploratory approach.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Trial Watch: Immunogenic cell death inducers for anticancer chemotherapy.
Pol J, Vacchelli E, Aranda F, Castoldi F, et al · · 2015 · cited 238× · PMID 26137404 · DOI 10.1080/2162402x.2015.1008866 -
UEG Week 2021 Oral Presentations
· 2021
Verify or expand the search:
- PubMed search for NCT02287129
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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- NCT07340567 — Personalizing Chemotherapy Selection After Surgery for Patients With Stage III Colorectal Cancer Using a Blood Test · Phase 3 · not yet recruiting
Other recruiting trials for Adenocarcinoma of the Esophagogastric Junction
Currently open trials in the same condition.
- NCT06681298 — A Multi-center, Two-arm, Phase 2 Clinical Study on the Perioperative Treatment of HER2-positive Resectable Esophagogastr · Phase 2 · active not recruiting
Other Technical University of Munich trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT02287129 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Technical University of Munich
- Last refreshed: 28 November 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02287129.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing