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NCT02284711: SALPOVA

Impact of Salpingectomy on Ovarian Reserve

Completed NA Last updated 2 September 2025
What this trial tests

NA trial testing Bipolar electric energy in Laparoscopic Salpingectomy in 96 participants. Completed in 16 October 2020.

Timeline
9 March 2015
Primary endpoint
16 October 2020
16 October 2020

Quick facts

Lead sponsorHospices Civils de Lyon
PhaseNA
StatusCompleted
Study typeINTERVENTIONAL
Allocationrandomized
Designparallel
Maskingnone
Primary purposeprevention
Enrollment96
Start date9 March 2015
Primary completion16 October 2020
Estimated completion16 October 2020
Sites1 location across France

Drugs / interventions tested

Conditions studied

Sponsor

Hospices Civils de Lyon — full company profile →

Who can join

18 and older, female only, with Laparoscopic Salpingectomy. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Epithelial cancer of the ovaries is the most severe form of gynecologic cancer; a significant proportion of ovarian cancers originate from the Fallopian tube. Guidelines therefore now recommend systematically associating prophylactic salpingectomy to benign hysterectomy. The principal objective of the present study is to assess the impact of salpingectomy on ovarian reserve by anti-Müllerian hormone (AMH) assay and calculating the Doppler index of vascular resistance in the ovarian vessels. The secondary objective is to compare ovarian reserve results between two coagulation techniques used in salpingectomy: bipolar electric energy versus ultrasound. The study design is single-center, prospective, before-and-after, with open randomization between two groups defined by coagulation technique.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Hysterectomy with opportunistic salpingectomy versus hysterectomy alone.
    van Lieshout LAM, Steenbeek MP, De Hullu JA, Vos MC, et al · · 2019 · cited 34× · PMID 31456223 · DOI 10.1002/14651858.cd012858.pub2

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