NCT02213731 is a NA clinical trial of Holter monitoring in Atrial Fibrillation, sponsored by Medtronic Cardiac Ablation Solutions.

Who is sponsoring NCT02213731?

NCT02213731 is sponsored by Medtronic Cardiac Ablation Solutions.

What drugs are being tested in NCT02213731?

Interventions in NCT02213731: Holter monitoring.

What condition does NCT02213731 study?

NCT02213731 studies Atrial Fibrillation.

Is NCT02213731 still recruiting?

NCT02213731 is currently completed. Last updated 13 February 2025.

Last reviewed 2025-02-13 · How we verify

NCT02213731

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Cryoballoon Ablation for Early Persistent Atrial Fibrillation (Cryo4 Persistent AF)

Completed NA Last updated 13 February 2025

What this trial tests

NA trial testing Holter monitoring in Atrial Fibrillation in 130 participants. Completed in 12 September 2017.

Timeline

8 December 2014

Primary endpoint
22 June 2017

12 September 2017

Quick facts

Lead sponsor	Medtronic Cardiac Ablation Solutions
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	treatment
Enrollment	130
Start date	8 December 2014
Primary completion	22 June 2017
Estimated completion	12 September 2017
Sites	14 locations across France, Greece, Germany

Drugs / interventions tested

Holter monitoring

Conditions studied

Atrial Fibrillation — all drugs for Atrial Fibrillation →

Sponsor

Medtronic Cardiac Ablation Solutions — full company profile →

Who can join

Adults 18 to 75, any sex, with Atrial Fibrillation. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The purpose of this clinical study is to assess the single procedure outcomes of using cryoballoon ablation without additional empirical lesions and/or complex fractionated electrogram (CFE) ablations for patients with early persistent atrial fibrillation (\<1 year from first diagnosis of persistent AF).

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Single-Procedure Outcomes and Quality-of-Life Improvement 12 Months Post-Cryoballoon Ablation in Persistent Atrial Fibrillation: Results From the Multicenter CRYO4PERSISTENT AF Trial.
Boveda S, Metzner A, Nguyen DQ, Chun KRJ, et al · · 2018 · cited 74× · PMID 30466850 · DOI 10.1016/j.jacep.2018.07.007
Cryoablation in persistent atrial fibrillation - a critical appraisal.
Tzeis S, Pastromas S, Sikiotis A, Andrikopoulos G. · · 2016 · cited 2× · PMID 27294840 · DOI 10.1007/s12471-016-0858-y

Verify or expand the search:

Other trials of Holter monitoring

Trials testing the same drug.

NCT05078125 — Electrocardiographic and Cardiac Magnetic Resonance Predictors of Ventricular Arrhythmias in Cardiomyopathic Patients · unknown
NCT04987723 — A Mechanistic Exploratory Study of AF-induced Cardiac Dysfunction and Symptoms · NA · completed
NCT04649034 — Intraventricular Stasis In Cardiovascular Disease · completed
NCT04617717 — Personalized Treatment for Patients With Premature Ventricular Beats · recruiting
NCT04090905 — Incidence of Post-operative Atrial Fibrillation Secondary to Abdominal Surgery · completed

Other recruiting trials for Atrial Fibrillation

Currently open trials in the same condition.

NCT07429214 — A Study of VARIPULSE Catheter and TRUPULSE Generator With VARIPULSE Pro Software in Participants With PAF or PsAF · NA · recruiting
NCT07271238 — Feasibility Study on the VERAFEYE Imaging and Navigation System for Guided Catheter Ablation Procedures · NA · recruiting
NCT07388108 — Atrial Dyssynchrony to Predict Arrhythmias in the Postoperative Setting of Cardiovascular Surgery. · recruiting
NCT07428967 — AV Node Ablation and CONDUCTion System Pacing for Atrial Fibrillation With Preserved Left Ventricular Function · NA · recruiting
NCT06650995 — AlEX-DHF: Ablation and Exercise in Diastolic Heart Failure · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT02213731 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Medtronic Cardiac Ablation Solutions
Last refreshed: 13 February 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02213731.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing