The MCS is comprised of questions about role-emotional, vitality/mental health and social functioning. Scores are standardized using a t-score transformation and normed to a U.S. population (based on a 1990 norm) of a score of 50 and a standard deviation of 10 where higher scores indicate better health outcomes.
The PCS provides emphasis on questions about general health, physical functioning and role playing and bodily pain. Scores are standardized using a t-score transformation and normed to a U.S. population (based on a 1990 norm) of a score of 50 and a standard deviation of 10 where higher scores indicate better health outcomes.
Baseline
Group
Value
95% CI
Mindfulness Meditation / Acupuncture
37.02
± 8.78
Gulf War Health Education
37.00
± 10.53
Endpoint
Group
Value
95% CI
Mindfulness Meditation / Acupuncture
39.41
± 8.78
Gulf War Health Education
35.69
± 10.99
Patient-Reported Outcomes Measurement Information System (PROMIS) Adult Short Form v1.0 - Pain Interference 8aPrimary· 8 weeks
An eight-item self-reported pain instrument designed at the National Institutes of Health (NIH) to measure the extent to which pain interferes with involvement in cognitive, emotional, physical, recreational, and social activities. Higher scores represent greater symptom severity. Range from 0 - 32.
Baseline
Group
Value
95% CI
Mindfulness Meditation / Acupuncture
17.90
± 8.96
Gulf War Health Education
17.47
± 9.30
Endpoint
Group
Value
95% CI
Mindfulness Meditation / Acupuncture
14.55
± 8.14
Gulf War Health Education
17.77
± 9.66
Patient-Reported Outcomes Measurement Information System Adult Short Form v1.0 - Fatigue 8aPrimary· 8 weeks
An 8-item NIH instrument consisting of eight items that asks about the experience and impact of fatigue. Higher scores represent greater symptom severity. Range from 0 - 32.
The SF-MPQ-2 measures continuous pain, intermittent pain, predominantly neuropathic pain, and affective descriptors. Higher scores indicate greater pain. Symptomatic pain on scale from 0 - 45.
Baseline
Group
Value
95% CI
Mindfulness Meditation / Acupuncture
16.88
± 8.75
Gulf War Health Education
17.01
± 9.58
Endpoint
Group
Value
95% CI
Mindfulness Meditation / Acupuncture
15.80
± 9.46
Gulf War Health Education
19.42
± 10.83
Multidimensional Fatigue Symptom Inventory - Short Form (MFSI-SF)Secondary· 8 weeks
The MFSI is a 30-item measurement tool that assesses the multidimensional nature of fatigue across five domains: general fatigue, physical fatigue, emotional fatigue, mental fatigue, and vigor. The range is from 24 to 96 with a higher score indicating higher levels of fatigue.
Baseline
Group
Value
95% CI
Mindfulness Meditation / Acupuncture
37.40
± 22.56
Gulf War Health Education
37.78
± 23.57
Endpoint
Group
Value
95% CI
Mindfulness Meditation / Acupuncture
27.69
± 23.15
Gulf War Health Education
38.17
± 27.59
Quality of Life in Neurological Disorders (Neuro-QoL)Secondary· 8 weeks
The items were selected from the 18 item Neuro-QOL Bank v1.0 - Applied Cognition - General Concerns. Scores range from 1 (very often) to 5 (none) for each cognitive symptom. Higher scores indicate better cognitive function. Range from 18 - 90.
Baseline
Group
Value
95% CI
Mindfulness Meditation / Acupuncture
48.85
± 17.41
Gulf War Health Education
49.11
± 17.77
Endpoint
Group
Value
95% CI
Mindfulness Meditation / Acupuncture
55.18
± 18.39
Gulf War Health Education
48.65
± 18.99
Patient Health Questionnaire-Depression Module (PHQ-9)Secondary· 8 weeks
The PHQ is a 9-item questionnaire, used to assess symptoms and functional impairment of depression to derive an overall severity score and a tentative depression diagnosis. Each item score ranges from 0-3 with higher scores indicating more severe depressive symptoms. Range from 0 - 27.
Baseline
Group
Value
95% CI
Mindfulness Meditation / Acupuncture
11.64
± 6.42
Gulf War Health Education
12.29
± 7.47
Endpoint
Group
Value
95% CI
Mindfulness Meditation / Acupuncture
9.76
± 6.86
Gulf War Health Education
13.32
± 8.44
Posttraumatic Symptom Checklist - Civilian Version (PCL-C)Secondary· 8 weeks
The PCL-C is a 17-item self-report checklist of PTSD symptoms based closely on the DSM-IV criteria with a range of 17-85. Higher scores indicate greater symptom expression.
Baseline
Group
Value
95% CI
Mindfulness Meditation / Acupuncture
31.95
± 18.86
Gulf War Health Education
31.63
± 22.04
Endpoint
Group
Value
95% CI
Mindfulness Meditation / Acupuncture
26.06
± 18.84
Gulf War Health Education
34.71
± 22.66
Perceived Stress Scale (PSS)Secondary· 8 weeks
The PSS is a 10-item scale that measures the degree to which situations in one's life over the past month are appraised as unpredictable, uncontrollable and overwhelming. Scores range from 0 to 40 with higher scores indicating higher perceived stress.
Baseline
Group
Value
95% CI
Mindfulness Meditation / Acupuncture
18.68
± 7.07
Gulf War Health Education
18.41
± 8.44
Endpoint
Group
Value
95% CI
Mindfulness Meditation / Acupuncture
17.24
± 6.81
Gulf War Health Education
19.17
± 7.30
The Brief Symptom Inventory (BSI)Secondary· 8 weeks
The Brief Symptom Inventory is a 53-item self-report inventory in which participants rate the extent to which they have been bothered (0 ="not at all" to 4="extremely") in the past week by various symptoms. Each subscale is averaged for all items, whereby a score of 4 would indicate the highest possible score.
Baseline
Group
Value
95% CI
Mindfulness Meditation / Acupuncture
1.12
± 0.73
Gulf War Health Education
1.16
± 0.86
Endpoint
Group
Value
95% CI
Mindfulness Meditation / Acupuncture
0.97
± 0.76
Gulf War Health Education
1.32
± 0.99
Sponsor's own description
The purpose of this study is to explore the effectiveness Gulf War Health Education (GWHE) and iRest Yoga Nidra (mindfulness meditation)/auricular (ear) acupuncture for Veterans with Gulf War Veterans' Illnesses (GWVI).
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
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Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by VA Office of Research and Development
Last refreshed: 1 September 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02180243.