Last reviewed · How we verify

NCT02130453

Accuracy of an Echo-Stress Protocol Using Regadenoson With Speckle Tracking

Completed Phase 4 Results posted Last updated 2 October 2024
What this trial tests

Phase 4 trial testing Regadenoson in Ischemia in 161 participants. Completed in 28 June 2024.

Timeline
30 September 2014
Primary endpoint
28 June 2024
28 June 2024

Quick facts

Lead sponsorM.D. Anderson Cancer Center
PhasePhase 4
StatusCompleted
Study typeINTERVENTIONAL
Allocationnon randomized
Designsingle group
Maskingsingle
Primary purposediagnostic
Enrollment161
Start date30 September 2014
Primary completion28 June 2024
Estimated completion28 June 2024
Sites1 location across United States

Drugs / interventions tested

Conditions studied

Sponsor

M.D. Anderson Cancer Center — full company profile →

Who can join

Adults 18 to 80, any sex, with Ischemia. Patients with the condition only — healthy volunteers not accepted.

Results — posted to ClinicalTrials.gov

Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.

Comparison of Accuracy of ReSTE Imaging to SPECT Imaging in Diagnosis of Ischemia Primary · 1 day

As primary analysis, paired test of equivalence used for proportions proposed by Tango to test equivalence of the two ischemia tests among tSPECT positive patients.

Positive RESTE proportion with positive angiogram
GroupValue95% CI
Experimental: ReSTE Cardiac Imaging0.15380.0151 – 0.2925
Positive nuclear stress test proportion with positive angiogram
GroupValue95% CI
Experimental: ReSTE Cardiac Imaging0.23080.0688 – 0.3928
Cardiac Event Rates After ReSTE and SPECT Imaging Secondary · 30 days

Cardiac events after ReSTE and SPECT imaging included myocardial infarction,heart failure, sudden cardiac death, cerebrovascular accident

GroupValue95% CI
Experimental: ReSTE Cardiac Imaging0

Sponsor's own description

The goal of this clinical research study is to compare regadenoson nuclear stress testing with echocardiography strain measurements (an ultrasound imaging method that measures hearts function) in detecting coronary artery disease.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other trials of Regadenoson

Trials testing the same drug.

Other recruiting trials for Ischemia

Currently open trials in the same condition.

Other M.D. Anderson Cancer Center trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02130453.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing