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NCT02033434: PRECINKT
Pre-hospital Care With Intra-Nasal Ketamine for Transport (PRECINKT): A Pilot Study
Phase 1 trial testing Intranasal Ketamine in Pain in 30 participants. Completed in 1 September 2017.
15 May 2016
Quick facts
| Lead sponsor | University of Calgary |
|---|---|
| Phase | Phase 1 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 30 |
| Start date | 1 March 2014 |
| Primary completion | 15 May 2016 |
| Estimated completion | 1 September 2017 |
| Sites | 1 location across Canada |
Drugs / interventions tested
- Intranasal Ketamine — full drug profile →
Conditions studied
- Pain — all drugs for Pain →
- Traumatic Limb Injury — all drugs for Traumatic Limb Injury →
Sponsor
University of Calgary
Who can join
Adults 18 to 79, any sex, with Pain or Traumatic Limb Injury. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The investigators hypothesize that intra-nasal ketamine, for analgesia of patients with moderate to severe pain in an alpine setting, will provide a clinically significant reduction in pain and provide an effective and feasible alternative to intravenous opioids. The investigators wish to know: 1. Is our study protocol feasible to study INK in a mountain, prehospital care environment? 2. What estimate can be made of recruitment rates? 3. Does studying the use of INK interfere with or delay care at Whistler/Blackcomb? 4. Is intra-nasal ketamine an effective and safe method for controlling pain in our study population and setting? 5. Does intranasal ketamine provide a clinically significant reduction in pain or do patients require additional IV narcotics for extraction? 6. Are there any significant changes in vital signs after administration of intra-nasal ketamine 7. Does the use of intra-nasal ketamine reduce time of patient extraction and transport in the alpine pre-hospital setting? 8. Are there any long term sequelae of INK at one week?
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT02033434
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Intranasal Ketamine
Trials testing the same drug.
- NCT03781817 — Intranasal Versus Intravenous Ketamine for Procedural Sedation in Children With Non-operative Fractures · Phase 4 · terminated
- NCT03053947 — Pain Free Laceration Repairs Using Intra-nasal Ketamine · Phase 2 · completed
Other recruiting trials for Pain
Currently open trials in the same condition.
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- NCT07454993 — The Effect of Music During Colonoscopy · NA · recruiting
Other University of Calgary trials
Trials by the same sponsor.
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- NCT07145645 — Topical Diclofenac vs.Oral Ibuprofen for MSK Pain in Children · Phase 3 · recruiting
- NCT07280325 — Moxie Self-Management and Education Support Program · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT02033434 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Calgary
- Last refreshed: 26 September 2019
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02033434.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing