NCT02030717 (ASA) is a Phase 2/Phase 3 clinical trial of klonidin in Pre- and Postoperative Analgesia, sponsored by Umeå University.

Who is sponsoring NCT02030717?

NCT02030717 is sponsored by Umeå University.

What drugs are being tested in NCT02030717?

Interventions in NCT02030717: klonidin, epidural anesthesia.

What condition does NCT02030717 study?

NCT02030717 studies Pre- and Postoperative Analgesia, Spinal Anesthesia, Renal Cell Carcinoma.

Is NCT02030717 still recruiting?

NCT02030717 is currently completed. Last updated 3 June 2015.

Last reviewed 2015-06-03 · How we verify

NCT02030717: ASA

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Randomized Study of Spinal Anesthesia Compared With Traditional Epidural Anesthesia Concerning Peroperative and Postoperative Pain After Open Nephrectomy in Patients With Renal Cell Carcinoma

Completed Phase 2/Phase 3 Last updated 3 June 2015

What this trial tests

Phase 2/Phase 3 trial testing klonidin in Pre- and Postoperative Analgesia in 120 participants. Completed in 1 May 2015.

Timeline

1 February 2012

Primary endpoint
1 May 2015

1 May 2015

Quick facts

Lead sponsor	Umeå University
Phase	Phase 2/Phase 3
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	treatment
Enrollment	120
Start date	1 February 2012
Primary completion	1 May 2015
Estimated completion	1 May 2015
Sites	1 location across Sweden

Drugs / interventions tested

klonidin — full drug profile →
epidural anesthesia — full drug profile →

Conditions studied

Pre- and Postoperative Analgesia — all drugs for Pre- and Postoperative Analgesia →
Spinal Anesthesia — all drugs for Spinal Anesthesia →
Renal Cell Carcinoma — all drugs for Renal Cell Carcinoma →

Sponsor

Umeå University

Who can join

18 and older, any sex, with Pre- and Postoperative Analgesia or Spinal Anesthesia. Patients with the condition only — healthy volunteers not accepted.

What's being measured

Primary outcomes are the specific endpoints the trial is designed to prove or disprove.

postoperative mobilisation index
Time frame: within the first 30 days (plus or minus 5 days) after surgery
Using a number of variables an index of mobilisation has been created; eg pain (10 graded scale), malaise, intravenous substitution, eating in dining room, Walking outside ward room, passage of stool, carrying urinary bladder catheter, can mobilise out of bed without help

Sponsor's own description

The study aim to study whether spinal anesthesia (using: bupivacain, morfin och klonidin) can be better than epidural anesthesia during and after open surgery for renal cell carcinoma. Per- and postoperative pain after spinal anesthesia with klonidin can be reduced and, thus, shorten the hospital stay and rehabilitation of the patients.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Spinal anaesthesia with clonidine: pain relief and earlier mobilisation after open nephrectomy - a randomised clinical trial.
Thurm M, Hultin M, Johansson G, Dahlin BI, et al · · 2022 · PMID 36177827 · DOI 10.1177/03000605221126883

Verify or expand the search:

Other Umeå University trials

Trials by the same sponsor.

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Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT02030717 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Umeå University
Last refreshed: 3 June 2015

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02030717.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing