NCT01992263 is a NA clinical trial of Vitamin D (600 IU) in Tuberculosis, sponsored by Cornell University.

Who is sponsoring NCT01992263?

NCT01992263 is sponsored by Cornell University.

What drugs are being tested in NCT01992263?

Interventions in NCT01992263: Vitamin D (600 IU), Vitamin D (2000 IU), Vitamin D (4000 IU), Placebo.

What condition does NCT01992263 study?

NCT01992263 studies Tuberculosis, Vitamin D, Immunity.

Is NCT01992263 still recruiting?

NCT01992263 is currently status unknown. Last updated 8 September 2020.

Last reviewed 2020-09-08 · How we verify

NCT01992263

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

A Trial of Vitamin D Supplementation Among Tuberculosis Patients in South India

Status unknown NA Last updated 8 September 2020

What this trial tests

NA trial testing Vitamin D (600 IU) in Tuberculosis in 200 participants. Status unknown.

Timeline

1 June 2021

Primary endpoint
1 September 2022

1 February 2023

Quick facts

Lead sponsor	Cornell University
Phase	NA
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	other
Enrollment	200
Start date	1 June 2021
Primary completion	1 September 2022
Estimated completion	1 February 2023
Sites	2 locations across United States, India

Drugs / interventions tested

Vitamin D (600 IU)
Vitamin D (2000 IU)
Vitamin D (4000 IU)
Placebo

Conditions studied

Tuberculosis — all drugs for Tuberculosis →
Vitamin D — all drugs for Vitamin D →
Immunity — all drugs for Immunity →

Sponsor

Cornell University

Who can join

Adults 18 to 60, any sex, with Tuberculosis or Vitamin D. Patients with the condition only — healthy volunteers not accepted.

What's being measured

Primary outcomes are the specific endpoints the trial is designed to prove or disprove.

Immune function
Time frame: One year
Immune responses will be assessed by the superoxide bursts and proteolytic capacities of macrophages and monocytes. Activity indexes will be assessed by comparing mean substrate and calibration fluorescence.
Cell-mediated immunological markers
Time frame: One year
T cells
Vitamin D status
Time frame: One year
Serum 25(OH)D concentrations

Sponsor's own description

The goal of this study is to understand the effects of vitamin D supplementation on immunological outcomes among patients with tuberculosis.

Publications & conference data

4 peer-reviewed publications reference this trial (live from Europe PMC):

Nutritional supplements for people being treated for active tuberculosis.
Grobler L, Nagpal S, Sudarsanam TD, Sinclair D. · · 2016 · cited 97× · PMID 27355911 · DOI 10.1002/14651858.cd006086.pub4
The Research Progress in Immunotherapy of Tuberculosis.
Mi J, Liang Y, Liang J, Gong W, et al · · 2021 · cited 27× · PMID 34869066 · DOI 10.3389/fcimb.2021.763591
Tuberculosis vaccines and therapeutic drug: challenges and future directions.
An Y, Ni R, Zhuang L, Yang L, et al · · 2025 · cited 24× · PMID 39841361 · DOI 10.1186/s43556-024-00243-6
Innovative Strategies in Drug Repurposing to Tackle Intracellular Bacterial Pathogens.
Lorente-Torres B, Llano-Verdeja J, Castañera P, Ferrero HÁ, et al · · 2024 · cited 6× · PMID 39335008 · DOI 10.3390/antibiotics13090834

Verify or expand the search:

Other recruiting trials for Tuberculosis

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Other Cornell University trials

Trials by the same sponsor.

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NCT06880510 — The Locus Coeruleus, Norepinephrine and Cognitive Aging · NA · recruiting
NCT06870526 — Feasibility of Online-supported Delivery Bringing Optimal Nutrition to Diverse Low-income Households With Children · NA · completed
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Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT01992263 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Cornell University
Last refreshed: 8 September 2020

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT01992263.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing