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NCT01940185
A Post-Approval Study of the LINX® Reflux Management System
trial testing LINX device in Gastroesophageal Reflux Disease (GERD) in 200 participants. Completed in 30 June 2023.
30 June 2023
Quick facts
| Lead sponsor | Torax Medical Incorporated |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 200 |
| Start date | 30 June 2012 |
| Primary completion | 30 June 2023 |
| Estimated completion | 30 June 2023 |
| Sites | 19 locations across United States |
Drugs / interventions tested
- LINX device
Conditions studied
- Gastroesophageal Reflux Disease (GERD) — all drugs for Gastroesophageal Reflux Disease (GERD) →
Sponsor
Torax Medical Incorporated
Who can join
21 and older, any sex, with Gastroesophageal Reflux Disease (GERD). Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
A Post-Approval Study of the LINX® Reflux Management System in a prospective, multicenter, single-arm study, with patients as their own control to monitor the safety and efficacy of the LINX implant procedure and device in a post-approval environment to supplement existing safety and efficacy data.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Long-term cost-effectiveness of medical, endoscopic and surgical management of gastroesophageal reflux disease.
Funk LM, Zhang JY, Drosdeck JM, Melvin WS, et al · · 2015 · cited 32× · PMID 25262216 · DOI 10.1016/j.surg.2014.05.027 -
Long-term (>5 Years) Outcomes after Magnetic Sphincter Augmentation.
Louie BE, Woldu HG, Bell RCW, Perry KA, et al · · 2026 · PMID 42117783 · DOI 10.1097/sla.0000000000006591
Verify or expand the search:
- PubMed search for NCT01940185
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of LINX device
Trials testing the same drug.
- NCT02429830 — LINX Reflux Management System in Subjects With GERD Who Have Previously Undergone a Laparoscopic Sleeve Gastrectomy · NA · completed
Other recruiting trials for Gastroesophageal Reflux Disease (GERD)
Currently open trials in the same condition.
- NCT02616302 — A Study to Check the Safety of Dexlansoprazole and Learn if it Can Treat Symptomatic Nonerosive Gastroesophageal Reflux · Phase 2 · recruiting
- NCT07174882 — Evaluation of the Clinical Course of NERD and Assessment of the Esophageal Mucosa Resistance · active not recruiting
- NCT05870163 — Post-Market Registry for the Evaluation of RefluxStop in GERD Treatment · recruiting
- NCT06862037 — Development of Machine Learning Models to Predict Postoperative GERD Symptom Resolution After Laparoscopic Nissen Fundop · active not recruiting
Other Torax Medical Incorporated trials
Trials by the same sponsor.
- NCT02429830 — LINX Reflux Management System in Subjects With GERD Who Have Previously Undergone a Laparoscopic Sleeve Gastrectomy · NA · completed
- NCT04007250 — FENIX™ Continence Restoration System Registry · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT01940185 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Torax Medical Incorporated
- Last refreshed: 5 January 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT01940185.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing