Last reviewed · How we verify
NCT05870163
Post-Market Registry for the Evaluation of RefluxStop in GERD Treatment
trial testing RefluxStop implantation in Gastroesophageal Reflux Disease (GERD) in 2,500 participants. Currently enrolling.
1 December 2025
Quick facts
| Lead sponsor | Implantica CE Reflux Ltd. |
|---|---|
| Status | Recruiting now |
| Study type | OBSERVATIONAL |
| Enrollment | 2,500 |
| Start date | 20 February 2023 |
| Primary completion | 1 December 2025 |
| Estimated completion | 31 December 2029 |
| Sites | 6 locations across Italy, Switzerland, Germany, Norway |
Drugs / interventions tested
- RefluxStop implantation
- Nissen fundoplication
Conditions studied
- Gastroesophageal Reflux Disease (GERD) — all drugs for Gastroesophageal Reflux Disease (GERD) →
Sponsor
Implantica CE Reflux Ltd.
Who can join
18 and older, any sex, with Gastroesophageal Reflux Disease (GERD). Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This post-market registry aims to assess safety and performance of RefluxStop™ in the treatment of Gastroesophageal Reflux Disease (GERD) in standard of care procedures.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT05870163
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Gastroesophageal Reflux Disease (GERD)
Currently open trials in the same condition.
- NCT02616302 — A Study to Check the Safety of Dexlansoprazole and Learn if it Can Treat Symptomatic Nonerosive Gastroesophageal Reflux · Phase 2 · recruiting
- NCT07174882 — Evaluation of the Clinical Course of NERD and Assessment of the Esophageal Mucosa Resistance · active not recruiting
- NCT06862037 — Development of Machine Learning Models to Predict Postoperative GERD Symptom Resolution After Laparoscopic Nissen Fundop · active not recruiting
Other Implantica CE Reflux Ltd. trials
Trials by the same sponsor.
- NCT07004439 — A Post-market Registry to Assess Safety and Performance of RefluxStop™ in the Treatment of GERD in General Hospital Prac · NA · not yet recruiting
- NCT07004400 — A Blinded Randomized Clinical Study of RefluxStop™ Compared With Nissen Fundoplication in the Treatment of GERD · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05870163 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Implantica CE Reflux Ltd.
- Last refreshed: 1 April 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05870163.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing