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NCT01932710
A Feasibility Study of Prophylactic White Blood Cell Transfusions
Phase 2 trial testing White Blood Cell Transfusion in Leukemia in 45 participants. Completed in 30 November 2016.
30 November 2016
Quick facts
| Lead sponsor | M.D. Anderson Cancer Center |
|---|---|
| Phase | Phase 2 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | prevention |
| Enrollment | 45 |
| Start date | 20 September 2013 |
| Primary completion | 30 November 2016 |
| Estimated completion | 30 November 2016 |
| Sites | 1 location across United States |
Drugs / interventions tested
- White Blood Cell Transfusion
Conditions studied
- Leukemia — all drugs for Leukemia →
Sponsor
M.D. Anderson Cancer Center — full company profile →
Who can join
Eligibility, any sex, with Leukemia. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Patients with leukemia often have low white blood cell counts after chemotherapy, which puts them at greater risk of infection. The standard of care for preventing infections is to give these patients antibiotic, antifungal, and antiviral drugs during the time that white blood cell counts are low. However, many patients still develop infections during chemotherapy. Radiated white blood cell transfusions are a standard treatment once a patient develops a severe infection. The goal of this clinical research study is to learn if giving white blood cell transfusions that are not radiated early in chemotherapy might delay or prevent infections in patients with leukemia. Researchers also want to learn more about the type and severity of any infections that do occur.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Granulocyte transfusions for treating infections in people with neutropenia or neutrophil dysfunction.
Estcourt LJ, Stanworth SJ, Hopewell S, Doree C, et al · · 2016 · cited 43× · PMID 27128488 · DOI 10.1002/14651858.cd005339.pub2 -
Granulocyte transfusions for preventing infections in people with neutropenia or neutrophil dysfunction.
Estcourt LJ, Stanworth S, Doree C, Blanco P, et al · · 2015 · cited 30× · PMID 26118415 · DOI 10.1002/14651858.cd005341.pub3
Verify or expand the search:
- PubMed search for NCT01932710
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT01932710 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by M.D. Anderson Cancer Center
- Last refreshed: 12 January 2018
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT01932710.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing