NCT01906801 is a Phase 4 clinical trial of Glucosamine sulfate in Osteoarthritis, sponsored by Ramathibodi Hospital.

Who is sponsoring NCT01906801?

NCT01906801 is sponsored by Ramathibodi Hospital.

What drugs are being tested in NCT01906801?

Interventions in NCT01906801: Glucosamine sulfate, Diacerein, Placebo (for Diacerein).

What condition does NCT01906801 study?

NCT01906801 studies Osteoarthritis, Glucosamine, Diacerein.

Is NCT01906801 still recruiting?

NCT01906801 is currently completed. Last updated 25 May 2017.

Last reviewed 2017-05-25 · How we verify

NCT01906801

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Clinical Efficacy of Glucosamine Plus Diacerein Versus Mono-therapy of Glucosamine

Completed Phase 4 Last updated 25 May 2017

What this trial tests

Phase 4 trial testing Glucosamine sulfate in Osteoarthritis in 148 participants. Completed in 1 October 2014.

Timeline

1 July 2013

Primary endpoint
1 October 2014

1 October 2014

Quick facts

Lead sponsor	Ramathibodi Hospital
Phase	Phase 4
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	triple
Primary purpose	treatment
Enrollment	148
Start date	1 July 2013
Primary completion	1 October 2014
Estimated completion	1 October 2014
Sites	1 location across Thailand

Drugs / interventions tested

Glucosamine sulfate — full drug profile →
Diacerein (DIACEREIN) — full drug profile →
Placebo (for Diacerein) — full drug profile →

Conditions studied

Osteoarthritis — all drugs for Osteoarthritis →
Glucosamine — all drugs for Glucosamine →
Diacerein — all drugs for Diacerein →

Sponsor

Ramathibodi Hospital

Who can join

50 and older, any sex, with Osteoarthritis or Glucosamine. Patients with the condition only — healthy volunteers not accepted.

What's being measured

Primary outcomes are the specific endpoints the trial is designed to prove or disprove.

pain visual analog scores
Time frame: 24 weeks

Sponsor's own description

The purpose of this study is to compare pain scores, WOMAC total and subscores, actual and change of joint space width and the rate of gastrointestinal side effects at 4, 8, 12, and 24 weeks between dual-therapy of diacerein and glucosamine versus a mono-therapy of glucosamine in OA patients

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

Pharmaceutical therapeutics for articular regeneration and restoration: state-of-the-art technology for screening small molecular drugs.
Chen Y, Sun H, Yao X, Yu Y, et al · · 2021 · cited 9× · PMID 34783870 · DOI 10.1007/s00018-021-03983-8
Efficacy of glucosamine plus diacerein versus monotherapy of glucosamine: a double-blind, parallel randomized clinical trial.
Kongtharvonskul J, Woratanarat P, McEvoy M, Attia J, et al · · 2016 · cited 9× · PMID 27729073 · DOI 10.1186/s13075-016-1124-9
Advances in Drug Delivery Science for Diacerein: Strategies to Enhance Solubility, Bioavailability, and Pharmacokinetic Performance.
Naseri M, Ghobakhlou S, Heidarizade N, Akbari ME, et al · · 2025 · PMID 41471053 · DOI 10.3390/pharmaceutics17121539

Verify or expand the search:

Other recruiting trials for Osteoarthritis

Currently open trials in the same condition.

NCT07404891 — Clinical Trial on the Efficacy and Safety of ALT001 in Osteoarthritis · NA · recruiting
NCT07118501 — A Prospective, Post-Market, Clinical Follow-up Study of the Incompass™ Total Ankle System · recruiting
NCT06631638 — EMPHASYS Cup Positioning in THA With Non-Invasive Navigation (Velys Hip Navigation (VHN)) · NA · recruiting
NCT07198750 — "Bimodal vs Unimodal High-Intensity Pulsed Electromagnetic Field Therapy in Older Adults With Knee Osteoarthritis" · NA · recruiting
NCT07006714 — Preoperative Correction of Vitamin D Deficiency in Total Joint Arthroplasty (TJA) · Phase 4 · active not recruiting

Other Ramathibodi Hospital trials

Trials by the same sponsor.

NCT07533604 — SnapDandCGMinType2Diabetes · NA · recruiting
NCT07377968 — Wearable Device to Promote CPAP Adherence in Obstructive Sleep Apnea (OSA) Patients · NA · not yet recruiting
NCT06983886 — The Effect of Local Infiltration of Tranexamic Acid on Postoperative Blood Loss in Orthognathic Surgery · Phase 1, PHASE2 · not yet recruiting
NCT06965088 — Comparison of Recurrence Rate of Keloid After Excision Between Intra-operative Steroid Injection and Steroid With Platel · Phase 2 · active not recruiting
NCT06453603 — Efficacy of Platelet-rich Plasma Injection Compare With Corticosteroid in Pes Anserinus Pain Syndrome · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT01906801 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Ramathibodi Hospital
Last refreshed: 25 May 2017

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT01906801.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing