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NCT01792037
the Effect of Single Dose of Etomidate Used During Emergency Intubation on Hemodynamics and Adrenal Cortex: a Randomized Clinical Trial
Phase 4 trial testing Etomidate in Adrenocortical Deficiency in 90 participants. Completed in 1 March 2013.
1 March 2013
Quick facts
| Lead sponsor | Istanbul University |
|---|---|
| Phase | Phase 4 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | crossover |
| Masking | single |
| Primary purpose | prevention |
| Enrollment | 90 |
| Start date | 1 December 2012 |
| Primary completion | 1 March 2013 |
| Estimated completion | 1 March 2013 |
| Sites | 1 location across Turkey (Türkiye) |
Drugs / interventions tested
- Etomidate (ETOMIDATE) — full drug profile →
- Midazolam (midazolam) — full drug profile →
- methylprednisolone (methylprednisolone) — full drug profile →
Conditions studied
- Adrenocortical Deficiency — all drugs for Adrenocortical Deficiency →
- Hemodynamic Instability — all drugs for Hemodynamic Instability →
Sponsor
Istanbul University
Who can join
Adults 25 to 65, any sex, with Adrenocortical Deficiency or Hemodynamic Instability. Patients with the condition only — healthy volunteers not accepted.
What's being measured
Primary outcomes are the specific endpoints the trial is designed to prove or disprove.
-
effect of use of steroid on adrenal cortex prior to single dose etomidate by comparing cortisol levels
Time frame: 24 hours
Sponsor's own description
we aim to evaluate the effects of single dose of etomidate or use of steroid prior to etomidate during emergency intubation on hemodynamics and adrenal cortex.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT01792037
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Etomidate
Trials testing the same drug.
- NCT04291521 — Prospective Study of Induction Medications Used in the Trauma RSI · not yet recruiting
- NCT07012902 — Relationship Between Remimazolam and Etomidate in Induction of General Anesthesia · EARLY_PHASE1 · not yet recruiting
- NCT06664138 — Comparison of Remimazolam and Etomidate As Induction Agents for Electroconvulsive Treatment · Phase 4 · completed
- NCT05277896 — Randomized Trial of Sedative Choice for Intubation · Phase 4 · completed
- NCT04934410 — Induction Agent and Incidence of Hypotension in Heart Failure Patients Undergoing LVAD-Implantation · unknown
Other Istanbul University trials
Trials by the same sponsor.
- NCT07472946 — Whole-Body Vibration Exercise in Patients With Parkinson's Disease · NA · not yet recruiting
- NCT07433894 — Scoliosis and Functional Outcomes in Children With Juvenile Idiopathic Arthritis · not yet recruiting
- NCT07420049 — Turkish Adaptation of the CTS-6 Evaluation Tool: A Validation and Reliability Study · not yet recruiting
- NCT07415967 — The Effect of a Dual-Task Technique-Based Exercise Program on Clinical Outcomes in Rotator Cuff Related Shoulder Pain · NA · recruiting
- NCT07473024 — pEEG-Guided Anesthesia and Behavioral Outcomes in Children · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT01792037 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Istanbul University
- Last refreshed: 23 August 2013
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT01792037.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing