Last reviewed · How we verify
Amidate (ETOMIDATE)
At a glance
| Generic name | ETOMIDATE |
|---|---|
| Sponsor | Pfizer |
| Drug class | General Anesthetic [EPC] |
| Target | Cytochrome P450 11B2, mitochondrial |
| Modality | Small molecule |
| Therapeutic area | Pain |
| Phase | FDA-approved |
| First approval | 1982 |
Approved indications
- General anesthesia
Common side effects
- Transient skeletal muscle movements
- Transient venous pain
- Hyperventilation
- Hypoventilation
- Apnea
- Laryngospasm
- Hiccup
- Snoring
- Hypertension
- Hypotension
- Tachycardia
- Bradycardia
Key clinical trials
- Effects of Different Drugs for Glottic Atomization on Postoperative Sore Throat After Thyroid Surgery (PHASE4)
- Randomized Trial of Sedative Choice for Intubation (PHASE4)
- A Study to Evaluate the Safety, Tolerability and Pharmacokinetics of KL0011034 Injection in Healthy Volunteers (PHASE1)
- Comparison of Anesthetic Techniques for Early Recovery After Ankle Arthroscopy (NA)
- Induction Agent Choice With Early Mortality and Prognostic Outcomes in Critically Ill Patients
- Dexmedetomidine and Myocardial Protection (NA)
- Propofol and Etomidate Admixtures Comparisons Trial (PEAC Trial) (PHASE3)
- Nalbuphine Timing Effects on Hemodynamics and Analgesia in Elderly Patients (PHASE4)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| FDA label | Mechanism, indications, dosing, boxed warnings, drug interactions |
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |