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NCT01684540: SNS01
Non-interventional Study: Application of Ectoin® Rhinitis Nasal Spray in Patients With Acute Rhinosinusitis
trial testing Medical Device, Drug-like in Sinusitis in 66 participants. Completed in 1 August 2012.
1 August 2012
Quick facts
| Lead sponsor | Bitop AG |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 66 |
| Start date | 1 February 2012 |
| Primary completion | 1 August 2012 |
| Estimated completion | 1 August 2012 |
| Sites | 6 locations across Germany |
Drugs / interventions tested
- Medical Device, Drug-like
- Sinupret forte — full drug profile →
Conditions studied
- Sinusitis — all drugs for Sinusitis →
Sponsor
Bitop AG — full company profile →
Who can join
18 and older, any sex, with Sinusitis. Patients with the condition only — healthy volunteers not accepted.
What's being measured
Primary outcomes are the specific endpoints the trial is designed to prove or disprove.
-
Changes in the symptoms of acute Rhinosinusitis assessed by the EPOS- Sinusitis-Symptom-Score
Time frame: day 1, day 7, day 14
Sponsor's own description
This is a comparative, open label, parallel group, non interventional study to further demonstrate the effectiveness and tolerability of Ectoin® Rhinitis Nasal Spray. In addition the effectiveness and safety shall be compared to a Sinupret forte. The patient applies Ectoin® Rhinitis Nasal Spray or takes Sinupret forte according to the instructions for use. The observation takes place over a period of 14 days. Response to treatment is recorded at day 7 and day 14 by the physician and in daily by the patient in a dairy.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
A prospective, controlled study of SNS01 (ectoine nasal spray) compared to BNO-101 (phytotherapeutic dragées) in patients with acute rhinosinusitis.
Eichel A, Wittig J, Shah-Hosseini K, Mösges R. · · 2013 · cited 19× · PMID 23621514 · DOI 10.1185/03007995.2013.800474
Verify or expand the search:
- PubMed search for NCT01684540
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Sinusitis
Currently open trials in the same condition.
- NCT03256773 — High Resolution Micro OCT Imaging · active not recruiting
Other Bitop AG trials
Trials by the same sponsor.
- NCT05699941 — Multicentre Post-market Study of Ectoin® Inhalation Solution in Treatment of Asthma. · NA · completed
- NCT04910906 — Non-Interventional Multicentre Post-market Study of Ectoin® Vaginal Gel for Symptomatic Treatment of Vaginal Atrophy · completed
- NCT04203810 — Effectiveness and Tolerability of Ectoin® Mouth and Throat Spray Althaea Honey (ERS09) · NA · completed
- NCT04097327 — Effect of Ectoin Dermatitis Cream 7% on Skin Hydration and Skin Barrier Function · completed
- NCT03975257 — Ectoin Lozenges (EHT02) in the Treatment of Oropharyngeal Allergic Symptoms · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT01684540 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Bitop AG
- Last refreshed: 27 January 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT01684540.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing