Who is sponsoring NCT04203810?

NCT04203810 is sponsored by Bitop AG.

What drugs are being tested in NCT04203810?

Interventions in NCT04203810: Ectoin® Mouth and Throat Spray Althaea Honey (ERS09), EMSER® Hals-und Rachenspray (throat spray).

What condition does NCT04203810 study?

NCT04203810 studies Sore Throat, Acute Pharyngitis, Cough.

Is NCT04203810 still recruiting?

NCT04203810 is currently completed. Last updated 28 July 2022.

Last reviewed 2022-07-28 · How we verify

NCT04203810

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Effectiveness and Tolerability of Ectoin® Mouth and Throat Spray Althaea Honey (ERS09)

Completed NA Last updated 28 July 2022

What this trial tests

NA trial testing Ectoin® Mouth and Throat Spray Althaea Honey (ERS09) in Sore Throat in 194 participants. Completed in 4 December 2020.

Timeline

14 January 2020

Primary endpoint
4 December 2020

4 December 2020

Quick facts

Lead sponsor	Bitop AG
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	treatment
Enrollment	194
Start date	14 January 2020
Primary completion	4 December 2020
Estimated completion	4 December 2020
Sites	12 locations across Germany

Drugs / interventions tested

Ectoin® Mouth and Throat Spray Althaea Honey (ERS09)
EMSER® Hals-und Rachenspray (throat spray)

Conditions studied

Sore Throat — all drugs for Sore Throat →
Acute Pharyngitis — all drugs for Acute Pharyngitis →
Cough — all drugs for Cough →

Sponsor

Bitop AG — full company profile →

Who can join

12 and older, any sex, with Sore Throat or Acute Pharyngitis. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The aim of this multicentre, actively controlled, randomized, open label, parallel group, prospective, comparator study is to collect data on the clinical effectiveness and tolerability of the medical device ERS09 compared to a well-established comparator spray in the symptomatic treatment of sore throat due to acute pharyngitis and dry cough.

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

Effectiveness and Tolerability of Ectoin<sup>®</sup> Mouth and Throat Spray Althaea Honey (ERS09) for Sore Throat due to Acute Pharyngitis and Dry Cough: A Multicentre, Actively Controlled, Open Label Study in Germany.
Roventa DLC, Pieper-Fürst U, Acikel C, Santos D, et al · · 2023 · cited 2× · PMID 37762768 · DOI 10.3390/jcm12185813
Abstracts, 16. Deutscher Allergiekongress, Dresden, 30. September-2. Oktober 2021
· 2021 · cited 1×
Abstracts of the 16th German Allergy Congress Dresden, September 30–October 2, 2021
· 2021

Verify or expand the search:

Other recruiting trials for Sore Throat

Currently open trials in the same condition.

NCT07486544 — Soaked Pharyngeal Packing Agents in Septoplasty · Phase 3 · recruiting
NCT07287293 — Endotracheal Tube Suctioning Versus No Suctioning During Emergence From General Anesthesia · NA · recruiting
NCT07517926 — Chewing Gum and Cold Gargle on Post-Bronchoscopy Symptoms · NA · recruiting
NCT06967896 — Different Models of Tracheal Catheters Are Used for Female Thyroid Glands · recruiting

Other Bitop AG trials

Trials by the same sponsor.

NCT05699941 — Multicentre Post-market Study of Ectoin® Inhalation Solution in Treatment of Asthma. · NA · completed
NCT04910906 — Non-Interventional Multicentre Post-market Study of Ectoin® Vaginal Gel for Symptomatic Treatment of Vaginal Atrophy · completed
NCT04097327 — Effect of Ectoin Dermatitis Cream 7% on Skin Hydration and Skin Barrier Function · completed
NCT03975257 — Ectoin Lozenges (EHT02) in the Treatment of Oropharyngeal Allergic Symptoms · NA · completed
NCT04021225 — Comparison of Ectoin® Containing Eye Drops and Ectoin® Containing Eye Spray With the Eye Spray Tears Again® · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04203810 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Bitop AG
Last refreshed: 28 July 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04203810.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing