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NCT01683084: TEDY
Study of the Effectiveness of Telmisartan in Slowing the Progression of Abdominal Aortic Aneurysms
Phase 4 trial testing Telmisartan in Abdominal Aortic Aneurysm in 22 participants. Completed in 10 November 2018.
10 November 2018
Quick facts
| Lead sponsor | Palo Alto Veterans Institute for Research |
|---|---|
| Phase | Phase 4 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | quadruple |
| Primary purpose | treatment |
| Enrollment | 22 |
| Start date | 19 September 2012 |
| Primary completion | 10 November 2018 |
| Estimated completion | 10 November 2018 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Telmisartan (TELMISARTAN) — full drug profile →
- Placebo
Conditions studied
- Abdominal Aortic Aneurysm — all drugs for Abdominal Aortic Aneurysm →
Sponsor
Palo Alto Veterans Institute for Research
Who can join
Adults 50 to 85, any sex, with Abdominal Aortic Aneurysm. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The purpose of this study is to determine if telmisartan is effective in slowing the progression of abdominal aortic aneurysms and reducing circulating concentrations of Abdominal Aortic Aneurysms (AAA) biomarkers.
Publications & conference data
6 peer-reviewed publications reference this trial (live from Europe PMC):
-
Abdominal aortic aneurysm: novel mechanisms and therapies.
Davis FM, Rateri DL, Daugherty A. · · 2015 · cited 126× · PMID 26352243 · DOI 10.1097/hco.0000000000000216 -
Pharmacologic Management of Aneurysms.
Lindeman JH, Matsumura JS. · · 2019 · cited 88× · PMID 30763216 · DOI 10.1161/circresaha.118.312439 -
Efficacy of Telmisartan to Slow Growth of Small Abdominal Aortic Aneurysms: A Randomized Clinical Trial.
Golledge J, Pinchbeck J, Tomee SM, Rowbotham SE, et al · · 2020 · cited 61× · PMID 32845283 · DOI 10.1001/jamacardio.2020.3524 -
Inhibition or deletion of angiotensin II type 1 receptor suppresses elastase-induced experimental abdominal aortic aneurysms.
Xuan H, Xu B, Wang W, Tanaka H, et al · · 2018 · cited 42× · PMID 28434702 · DOI 10.1016/j.jvs.2016.12.110 -
Current Status and Perspectives on Pharmacologic Therapy for Abdominal Aortic Aneurysm.
Yoshimura K, Morikage N, Nishino-Fujimoto S, Furutani A, et al · · 2018 · cited 37× · PMID 29284386 · DOI 10.2174/1389450119666171227223331 -
TElmisartan in the management of abDominal aortic aneurYsm (TEDY): The study protocol for a randomized controlled trial.
Morris DR, Cunningham MA, Ahimastos AA, Kingwell BA, et al · · 2015 · cited 27× · PMID 26081587 · DOI 10.1186/s13063-015-0793-z
Verify or expand the search:
- PubMed search for NCT01683084
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other recruiting trials for Abdominal Aortic Aneurysm
Currently open trials in the same condition.
- NCT07476196 — Poland-Italy Aortic Research Bridge Real World Registry · recruiting
- NCT07473102 — PET Imaging of MMP Activation in AAA: Clinical Component · EARLY_PHASE1 · recruiting
- NCT06451315 — REGISTRY on the Implementation of Artificial Intelligence in the Automatic Analysis of Vascular Network Segmentation · recruiting
- NCT06001918 — Nectero EAST System Clinical Study · Phase 2, PHASE3 · recruiting
- NCT06008613 — 3D Holographic Guidance, Navigation, and Control for Endovascular Aortic Repair · NA · active not recruiting
Other Palo Alto Veterans Institute for Research trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT01683084 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Palo Alto Veterans Institute for Research
- Last refreshed: 26 May 2020
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT01683084.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing